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Official Full Name B-cell CLL/lymphoma 3
Background The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Synonyms BCL4; D19S37; BCL3; B-cell lymphoma 3 protein; BCL-3; OTTHUMP00000200151; OTTHUMP00000200152; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; chronic lymphatic leukemia protein
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BCL3-151H Recombinant Human BCL3 Mammalian Cell His
    Human BCL3-157H Recombinant Human BCL3 Protein, GST-tagged Wheat Germ GST
    Human BCL3-1724H Recombinant Human BCL3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BCL3-8481HCL Recombinant Human BCL3 293 Cell Lysate HEK293 N/A
    Mouse Bcl3-1859M Recombinant Mouse Bcl3 protein, His & T7-tagged E.coli His/T7
    Mouse BCL3-2350M Recombinant Mouse BCL3 Protein Mammalian Cell His
    Mouse Bcl3-700M Recombinant Mouse Bcl3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Bcl3-1860R Recombinant Rat Bcl3 protein, His & T7-tagged E.coli His/T7

    BCL3 involved in several pathways and played different roles in them. We selected most pathways BCL3 participated on our site, such as TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TNF signaling pathway MAPK9; CCL5; PIK3CA; IL6; CXCL3; MMP9; IL15; RPS6KA4; BAG4; RPS6KA5

    BCL3 has several biochemical functions, for example, DNA binding, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL3 itself. We selected most functions BCL3 had, and list some proteins which have the same functions with BCL3. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HER7; ASH1L; ZKSCAN6; ZFP541; ZFP82; HIST2H4A; MYBL2B; ASCL3; ZNF620; HMGB2A
    protein binding RNF34; EIF2AK2; TSR2; HOPX; HERPUD1; PEX5; HCLS1; CTDSP2; DSCC1; HSPBAP1
    protein binding, bridging ST13; CNTLN; MMS19; FSCN1A; FLRT2; CUX1; WWC1; NMD3; FSCN2B; TRIM5
    transcription factor activity, sequence-specific DNA binding FOXD3; ZFP28; TA; HELT; HEYL; MEOX2; GTF3A; PRRXL1; ETV5; ARNT
    transcription factor binding MED12L; FOXA3; ZBTB49; NCOA2; SMAD2; CEBPG; STAT3; PURA; DDX3X; ARNT

    BCL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL3.


    Komai, K; Niwa, Y; et al. Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. FEBS LETTERS 589:738-743(2015).
    Chen, H; Zhang, Q; et al. Patterning of light-extraction nanostructures on sapphire substrates using nanoimprint and ICP etching with different masking materials. NANOTECHNOLOGY 26:-(2015).

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