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Official Full Name B-cell CLL/lymphoma 9
Background BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
Synonyms BCL9; B-cell CLL/lymphoma 9; LGS; B-cell CLL/lymphoma 9 protein; bcl-9; protein legless homolog; B-cell lymphoma 9 protein;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BCL9-10190H Recombinant Human BCL9, GST-tagged E.coli GST
    Human BCL9-1243H Recombinant Human BCL9 protein, His & T7-tagged E.coli His/T7
    Human BCL9-168H Recombinant Human BCL9 Protein, GST-tagged Wheat Germ GST
    Mouse Bcl9-1244M Recombinant Mouse Bcl9 protein, His & T7-tagged E.coli His/T7
    Mouse BCL9-2356M Recombinant Mouse BCL9 Protein Mammalian Cell His
    Rhesus Macaque BCL9-527R Recombinant Rhesus monkey BCL9 Protein, His-tagged Mammalian Cell His
    Zebrafish BCL9-1443Z Recombinant Zebrafish BCL9 Mammalian Cell His

    BCL9 involved in several pathways and played different roles in them. We selected most pathways BCL9 participated on our site, such as Deactivation of the beta-catenin transactivating complex, Formation of the beta-catenin:TCF transactivating complex, Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Deactivation of the beta-catenin transactivating complex C; TLE3; CBY1; SOX13; BCL9L; SOX7; CTBP1; SOX32; SOX6; RBBP5
    Formation of the beta-catenin:TCF transactivating complex CDC73; TLE2; BCL9; H3F3D; TLE4; TLE1; SMARCA4; RBBP5; TLE3B; H3F3B.1
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription SALL4; T; CBY1; ZCCHC12; IGF2BP1; TLE2; AES; MYOG; TLE1; BCL9
    Signal Transduction ABHD12; AKAP13; CLIP3; CCDC88C; CDC37; OTUD7B; OPN4; CDC42EP1B; GPBAR1; ARAP2
    Signaling by Wnt FMNL3; SOX9B; CCDC88C; WNT8-2; GPR177; PRICKLE1B; BCL9; DACT1; RSPO2; LGR5
    TCF dependent signaling in response to WNT RNF43; WIF1; RNF146; SRY; BCL9L; USP34; TNKS2; SOX4B; ZNRF3; RSPO4
    Wnt Signaling Pathway NetPath MARK2; BRD7; TFAP2A; HIPK2; NR5A1; CRYBB2; TAX1BP3; CSNK2A1P; SALL1; TCF4

    BCL9 has several biochemical functions, for example, beta-catenin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL9 itself. We selected most functions BCL9 had, and list some proteins which have the same functions with BCL9. You can find most of the proteins on our site.

    Function Related Protein
    beta-catenin binding DACT1; MED12L; DACT3; SHROOM2; DVL3; APC2; PTPRU; CD2AP; FAM123B; SLC9A3R2
    protein binding USP6; VARS2; RAMP1; MAPKAPK3; PIDD1; UBE2I; RC3H2; NUBP1; CCDC55; ICA1L

    BCL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL9.

    PYGO1; PYGO2; CDC73; arm; CTNNB1; h3_peptide_fragment; TCF4; Ctnnb1

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