Recombinant Human BCL9, GST-tagged

• Cat.No.: BCL9-10190H
• Product Overview: Recombinant Human BCL9 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 8-340a.a.
• Description: BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: BCL9 B-cell CLL/lymphoma 9 [ Homo sapiens ]
• Official Symbol: BCL9
• Synonyms: BCL9; B-cell CLL/lymphoma 9; B-cell CLL/lymphoma 9 protein; bcl-9; protein legless homolog; B-cell lymphoma 9 protein; LGS; MGC131591
• Gene ID: 607
• mRNA Refseq: NM_004326
• Protein Refseq: NP_004317
• MIM: 602597
• UniProt ID: O00512
• Chromosome Location: 1q21
• Pathway: Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem
• Function: protein binding