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BIRC8

Official Full Name

baculoviral IAP repeat containing 8
Background

Protects against apoptosis mediated by BAX.
Synonyms

BIRC8; baculoviral IAP repeat containing 8; ILP2; ILP-2; hILP2; baculoviral IAP repeat-containing protein 8; IAP-like protein 2; baculoviral IAP repeat-containing 8; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis;

Type:
Recombinant Proteins
Cell & Tissue Lysates

Species :
Human

Source :
E.coli
Wheat Germ

Tag :
GST
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	BIRC8-234H	Recombinant Human BIRC8 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	BIRC8-171HCL	Recombinant Human BIRC8 cell lysate		N/A	Inquiry
Human	BIRC8-10235H	Recombinant Human BIRC8, GST-tagged	E.coli	GST	$319.00 / 25ug
Human	BIRC8-233H	Recombinant Human BIRC8 Protein, GST-tagged	Wheat Germ	GST	Inquiry

Involved Pathway
Protein Function
Interacting Protein
BIRC8 Related Articles

BIRC8 involved in several pathways and played different roles in them. We selected most pathways BIRC8 participated on our site, such as Apoptosis, Pathways in cancer, Small cell lung cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Apoptosis	TNFRSF10D;BCAP31;PRKAR1A;DSG3;YWHAQ;IL1B2;MAP3K14;PRKACBB;IRF2A
Pathways in cancer	RAC3;IL6;GNB4;TGFB2;MET;MAPK1;MAPK9;TGFBR1;FOXO1
Small cell lung cancer	CCNE2;FN1;PIAS2;ITGA2;BCL2;TP53;TRAF4;ITGAV;LAMA1
Toxoplasmosis	TGFB3;BIRC3;TLR4;IFNGR1;LAMB4;LAMB3;HSPA1L;HLA-DRB3;HLA-DMA
Ubiquitin mediated proteolysis	MID1;CBL;UBE2E3;UBR5;PRP19;RCHY1;TRIM37;CUL4B;UBE2Z

BIRC8 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, ubiquitin-protein transferase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC8 itself. We selected most functions BIRC8 had, and list some proteins which have the same functions with BIRC8. You can find most of the proteins on our site.

Function	Related Protein
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	C1QL4L;NAIP1;BIRC8;PRDX3;DPEP1;SNCA;BIRC3;XIAP;LEF1
ubiquitin-protein transferase activity	UBE2K;TRIM17;WDSUB1;PAX6;UBE2B;FEM1B;FBXO25;UBE2D1;UBE2A
zinc ion binding	MMP12;NSMCE2;SQSTM1;RORAB;SETMAR;ZNRF2A;LIG3;RXRB;ZBTB32

BIRC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC8.

HIP2; UBE2D1; UBE2E1; UBE2D3; UBE2N; UBE2D2; UBE2V1; UBE2W; UBE2D4

Barathan, M; Gopal, K; et al. Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. APOPTOSIS 20:466-480(2015).

Glodkowska-Mrowka, E; Solarska, I; et al. Differential expression of BIRC family genes in chronic myeloid leukaemia-BIRC3 and BIRC8 as potential new candidates to identify disease progression. BRITISH JOURNAL OF HAEMATOLOGY 164:740-742(2014).