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BRD7

Official Full Name

bromodomain containing 7
Overview

This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Synonyms

BRD7; bromodomain containing 7; bromodomain-containing protein 7; BP75; CELTIX1; 75 kDa bromodomain protein; BRD 7; BRD7_HUMAN; bromodomain containing protein 7; CELTIX 1; NAG4; Protein CELTIX-1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E. coli
E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
Fc
Avi
Myc
DDK
N
C
FLAG
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	BRD7-2836H	Recombinant Human BRD7 protein, His&FLAG-tagged	E. coli	N-His&C-FLAG	129-236 aa	Inquiry
Human	BRD7-12H	Recombinant Human BRD7, GST-tagged	E.coli	GST		Inquiry
Human	BRD7-13H	Recombinant Human BRD7, GST-tagged	Wheat Germ	GST		Inquiry
Human	BRD7-14H	Recombinant Human BRD7, GST-tagged	E.coli	GST		Inquiry
Human	BRD7-8411HCL	Recombinant Human BRD7 293 Cell Lysate	HEK293	Non		Inquiry
Human	BRD7-2441H	Recombinant Human BRD7 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	BRD7-576HF	Recombinant Full Length Human BRD7 Protein, GST-tagged	In Vitro Cell Free System	GST	651 amino acids	Inquiry
Mouse	BRD7-2486M	Recombinant Mouse BRD7 Protein	Mammalian Cell	His		Inquiry
Mouse	BRD7-1086M	Recombinant Mouse BRD7 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	BRD7-1086M-B	Recombinant Mouse BRD7 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Brd7-1890M	Recombinant Mouse Brd7 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Zebrafish	BRD7-12545Z	Recombinant Zebrafish BRD7	Mammalian Cell	His		Inquiry
Chicken	BRD7-1274C	Recombinant Chicken BRD7	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

BRD7 involved in several pathways and played different roles in them. We selected most pathways BRD7 participated on our site, such as Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Wnt Signaling Pathway NetPath	MTAP1B;PAX2;TAX1BP3;TCF4;ROR2;HIPK2;BRD7;MAP1B;MARK2

BRD7 has several biochemical functions, for example, histone binding, lysine-acetylated histone binding, p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD7 itself. We selected most functions BRD7 had, and list some proteins which have the same functions with BRD7. You can find most of the proteins on our site.

Function	Related Protein
histone binding	NFKBIL2;RAG1;RNF168;PIH1D1;DTX3L;UHRF2;SART3;ANP32B;CHAF1B
lysine-acetylated histone binding	TAF1L;TAF1;PSME4;BAZ2A;BRD4;BRD2;PHIP;TRIM24;CARM1
p53 binding	ANKRD1;SMARCA4;CDK5;EP300;ZNF385D;AXIN1;ZMAT4;KDM1A;PLK3
protein binding	FGF7;UNG;MRPL27;CLCNKB;USO1;CIDEB;XRCC2;ZP3;SLC52A2
transcription coactivator activity	KAT2B;USP22;GTF2A2;NPM1;ABT1;NEUROG3;GRIP1;NACA;NFKBIB
transcription corepressor activity	NPAT;ATF7IP;CBFA2T3;ZBTB32;HDAC7;PBXIP1;LMCD1;ANKRD1;SSX4
transcription factor binding	IGHMBP2;EPN1;SOST;E2F2;HOXA7;DAXX;SORBS3;GTF2A1;FOXO4
transcription regulatory region DNA binding	CDK5RAP2;FOXI1;PROX1;IKZF3;ZNF217;FOXM1;ASH2L;GATA4;JUND

BRD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD7.

TP53; HNRNPUL1; EP300; ms-417; PRKAR1A; HIST2H4B; HIST1H3D