BRD7

  • Official Full Name

    bromodomain containing 7

  • Overview

    This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

  • Synonyms

    BRD7;bromodomain containing 7;bromodomain-containing protein 7;BP75;CELTIX1;75 kDa bromodomain protein;BRD 7;BRD7_HUMAN;bromodomain containing protein 7;CELTIX 1;NAG4;Protein CELTIX-1

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • Flag
  • His
  • GST
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
BRD7-2836H Recombinant Human BRD7 protein, His&FLAG-tagged E.coli Human Flag&His 129-236 aa
BRD7-12545Z Recombinant Zebrafish BRD7 Mammalian Cells Zebrafish His
BRD7-1274C Recombinant Chicken BRD7 Mammalian Cells Chicken His
BRD7-12H Recombinant Human BRD7, GST-tagged E.coli Human GST 129-252 a.a.
BRD7-13H Recombinant Human BRD7, GST-tagged Wheat Germ Human GST
BRD7-14H Recombinant Human BRD7, GST-tagged E.coli Human GST 129-236 a.a.
BRD7-2486M Recombinant Mouse BRD7 Protein Mammalian Cells Mouse His
BRD7-8411HCL Recombinant Human BRD7 293 Cell Lysate HEK293 Human Non
BRD7-1086M Recombinant Mouse BRD7 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
BRD7-1086M-B Recombinant Mouse BRD7 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Brd7-1890M Recombinant Mouse Brd7 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
BRD7-2441H Recombinant Human BRD7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
BRD7-576HF Recombinant Full Length Human BRD7 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 651 amino acids

    Involved Pathway

    BRD7 involved in several pathways and played different roles in them. We selected most pathways BRD7 participated on our site, such as Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt Signaling Pathway NetPath ROR2,MARK2,NR5A1,BCL9,CRYBB2,ANKRD6,MTAP1B,TFAP2A,PAX2,SOX1

    Protein Function

    BRD7 has several biochemical functions, for example, histone binding,lysine-acetylated histone binding,p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD7 itself. We selected most functions BRD7 had, and list some proteins which have the same functions with BRD7. You can find most of the proteins on our site.

    Function Related Protein
    transcription coactivator activity NCOA4,PRDM16,PARK7,SOX10,MED27,SMARCA2,AIP,VGLL2,TUBB3,GATA4
    histone binding HIST1H4I,SIRT1,PRKCB,RNF168,ELP2,NPM1,PKN1,HIST1H3D,NCL,LEF1
    protein binding PMP22,DHX30,SNAPC5,RANGAP1,BLOC1S2,CA8,MYO18A,C5,TUB,DHX40
    transcription corepressor activity ZHX1,SNW1,HIRA,ERF,NR0B1,DRAP1,LDB1,SETD8,MXI1,ZNF136
    transcription factor binding PIK3R1,TAF7L,ZEB1,JUNBB,HOXA7,CEBPG,NFKBIA,DAXX,PAXBP1,TCF7L2
    transcription regulatory region DNA binding JUN,ZFP382,SERPINB1A,ZNF649,ZFP639,DHX36,GATA5,OVOL2,KDM1A,CTCFL
    p53 binding BRD4,SIRT1,ZFP385C,BCL2L12,DAXX,DUSP26,MAPKAPK5,RNF34,EHMT1,ZFP346
    lysine-acetylated histone binding BRD4,BRD2,ATAD2B,PHIP,TAF1L,BAZ2A,PSME4,TRIM24,TAF1,PSME4B

    Interacting Protein

    BRD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD7.

    TP53;HNRNPUL1;EP300;ms-417;PRKAR1A;HIST2H4B;HIST1H3D

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