| Official Full Name | bromodomain containing 7 |
| Background | This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. |
| Synonyms | BRD7; bromodomain containing 7; bromodomain-containing protein 7; BP75; CELTIX1; 75 kDa bromodomain protein; BRD 7; BRD7_HUMAN; bromodomain containing protein 7; CELTIX 1; NAG4; Protein CELTIX-1 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
BRD7 involved in several pathways and played different roles in them. We selected most pathways BRD7 participated on our site, such as Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt Signaling Pathway NetPath | PAX2; MTAP1B; NR5A1; MARK2; BCL9; TAX1BP3; TFAP2A; ANKRD6; BRD7; TCF4 |
BRD7 has several biochemical functions, for example, histone binding, lysine-acetylated histone binding, p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD7 itself. We selected most functions BRD7 had, and list some proteins which have the same functions with BRD7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| histone binding | SERPINB1A; ANP32E; RAG1; MYSM1; ATAD2; HIST1H3G; HIST1H4M; Ctsl; HIST2H3C1; L3MBTL1 |
| lysine-acetylated histone binding | BRDT; ATAD2B; BRD3; CARM1; BRD2; TAF1; SMARCA4; TAF1L; BRD9; BRD7 |
| p53 binding | TP63; TAF1; USP10; TAF3; TP53; ZNF385C; MAPKAPK5; SMARCA4; CDKN2A; RCHY1 |
| protein binding | TOE1; MAP3K7IP3; NUP37; TMEM79; OLA1; GSK3A; SIGLEC8; NEDD4; NOS1AP; TAF13 |
| transcription coactivator activity | CCNE1; RUNX1; SAP130; FUS; MAML2; USP22; JUNBA; PRPF6; MYOD1; NFKBIB |
| transcription corepressor activity | E2F6; LIMD1; MNT; TDP2; CITED2; ARHGAP35; TGIF1; TLE2; TRIM22; SSX2 |
| transcription factor binding | DACT2; CTBP1; EP300; APBB2; MSX2; E2F1; FOXF2; BPTF; ENPP2; MED12 |
| transcription regulatory region DNA binding | WNT11; IKZF1; SNCA; TFAP4; REST; TAF7; BASP1; GLI1; TAF9; TCF7L1B |
BRD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD7.
TP53; HNRNPUL1; EP300; ms-417; PRKAR1A; HIST2H4B; HIST1H3D
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