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Recombinant Human BRD7, GST-tagged

Cat.No. : BRD7-13H
Product Overview : Recombinant Human BRD7 full-length ORF (1 a.a. - 651 a.a.) fussed with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 97.13 kDa
AA Sequence : MGKKHKKHKSDKHLYEEYVEKPLKL VLKVGGNEVTELSTGSSGHDSSLFE DKNDHDKHKDRKRKKRKKGEKQIPG EEKGRKRRRVKEDKKKRDRDRVENE AEKDLQCHAPVRLDLPPEKPLTSSL AKQEEVEQTPLQEALNQLMRQLQRK DPSAFFSFPVTDFIAPGYSMIIKHP MDFSTMKEKIKNNDYQSIEELKDNF KLMCTNAMIYNKPETIYYKAAKKLL HSGMKILSQERIQSLKQSIDFMADL QKTRKQKDGTDTSQSGEDGGCWQRE REDSGDAEAHAFKSPSKENKKKDKD MLEDKFKSNNLEREQEQLDRIVKES GGKLTRRLVNSQCEFERRKPDGTTT LGLLHPVDPIVGEPGYCPVRLGMTT GRLQSGVNTLQGFKEDKRNKVTPVL YLNYGPYSSYAPHYDSTFANISKDD SDLIYSTYGEDSDLPSDFSIHEFLA TCQDYPYVMADSLLDVLTKGGHSRT LQEMEMSLPEDEGHTRTLDTAKEME ITEVEPPGRLDSSTQDRLIALKAVT NFGVPVEVFDSEEAEIFQKKLDETT RLLRELQEAQNERLSTRPPPNMICL LGPSYREMHLAEQVTNNLKELAQQV TPGDIVSTYGVRKAMGISIPSPVME NNFVDLTEDTEEPKKTDVAECGPGG S
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : BRD7 bromodomain containing 7 [ Homo sapiens ]
Official Symbol : BRD7
Synonyms : BP75; NAG4; CELTIX1; bromodomain-containing protein 7; 75 kDa bromodomain protein; protein CELTIX-1
Gene ID : 29117
mRNA Refseq : NM_001173984
Protein Refseq : NP_001167455
UniProt ID : Q9NPI1
Chromosome Location : 16q12
Pathway : Wnt Signaling Pathway NetPath, organism-specific biosystem
Function : histone binding; lysine-acetylated histone binding; p53 binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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