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CANT1

  • Official Full Name

    calcium activated nucleotidase 1

  • Overview

    This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.
  • Synonyms

    CANT1; calcium activated nucleotidase 1; soluble calcium-activated nucleotidase 1; SCAN 1; SHAPY; Soluble Ca Activated Nucleotidase; isozyme 1; Apyrase; Apyrase homolog; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase; CANT 1; CANT1_HUMAN; Putative MAPK activating protein PM09; Putative MAPK-activating protein PM09; Putative NF kappa B activating protein 107; Putative NF-kappa-B-activating protein 107; SCAN-1; Soluble Ca activated nucleotidase isozyme 1; Soluble calcium activated nucleotidase 1; Soluble calcium activated nucleotidase SCAN 1; soluble Ca-activated nucleotidase, isozyme 1; soluble calcium-activated nucleotidase SCAN-1; Ca2+-dependent endoplasmic; DBQD; SCAN1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CANT1-489H Recombinant Human CANT1 Protein, His-tagged HEK293 His
Human CANT1-1338H Recombinant Human Calcium Activated Nucleotidase 1, His-tagged E.coli His
Human CANT1-7348H Recombinant Human CANT1 protein, hFc-tagged HEK293 hFc Gly80-Ile401
Human CANT1-0348H Recombinant Human CANT1 Protein, GST-Tagged Wheat Germ GST
Human CANT1-1597HCL Recombinant Human CANT1 cell lysate Human Cell N/A
Human CANT1-585H Recombinant Human CANT1 Protein, His-tagged E.coli His Ile107~Phe400
Human CANT1-1083H Recombinant Human CANT1 Protein (Ile107-Phe400), His tagged E.coli His Ile107-Phe400
Human CANT1-4712H Recombinant Human CANT1 protein, GST-tagged E.coli GST 80-397aa
Human CANT1-4713H Recombinant Human CANT1 protein, His-tagged E.coli His 80-397aa
Human CANT1-2806HF Recombinant Full Length Human CANT1 Protein, GST-tagged In Vitro Cell Free System GST 401 amino acids
Mouse CANT1-2685M Recombinant Mouse CANT1 Protein Mammalian Cell His
Mouse CANT1-1209M-B Recombinant Mouse CANT1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cant1-586M Recombinant Mouse Cant1 Protein, His-tagged E.coli His Val111~Ile403
Mouse CANT1-1209M Recombinant Mouse CANT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CANT1-1113R Recombinant Rat CANT1 Protein Mammalian Cell His
Rat CANT1-777R Recombinant Rat CANT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CANT1-777R-B Recombinant Rat CANT1 Protein Pre-coupled Magnetic Beads HEK293
Chicken CANT1-3222C Recombinant Chicken CANT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CANT1 Related Articles
  • CANT1 Related Research Area

CANT1 involved in several pathways and played different roles in them. We selected most pathways CANT1 participated on our site, such as Purine metabolism, Pyrimidine metabolism, UTP and CTP dephosphorylation II, which may be useful for your reference. Also, other proteins which involved in the same pathway with CANT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismNME3;NT5C2B;POLA2;PDE7A;PAPSS2;ENTPD3;NME2;GUK1B;CECR1A
Pyrimidine metabolismUPP2;NME2A;NT5C1B;CANT1;NME1-NME2;POLR2GL;CANT1A;PNP5A;NME2B.2
UTP and CTP dephosphorylation II

CANT1 has several biochemical functions, for example, calcium ion binding, guanosine-diphosphatase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CANT1 itself. We selected most functions CANT1 had, and list some proteins which have the same functions with CANT1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingANXA5;SLC25A25A;AOC3;FKBP7;PADI2;DLK2;SYT12;ITSN2;MYL12B
guanosine-diphosphatase activityCANT1;CANT1A;ENTPD5;CANT1B
signal transducer activityGNG2;PLCL2;GNB2;HTR5AL;GOLT1B;GNA15;TAAR2;OLFCG3;GNG4
uridine-diphosphatase activityCANT1B;ENTPD4;CANT1A;ENTPD5;CANT1;ENTPD6

CANT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CANT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CANT1.

Manque, PA; Woehlbier, U; et al. Identification and Characterization of a Novel Calcium-Activated Apyrase from Cryptosporidium Parasites and Its Potential Role in Pathogenesis. PLOS ONE 7:-(2012).
Zarlenga, DS; Nisbet, AJ; et al. A calcium-activated nucleotidase secreted from Ostertagia ostertagi 4th-stage larvae is a member of the novel salivary apyrases present in blood-feeding arthropods. PARASITOLOGY 138:333-343(2011).
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