cbr3

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cbr3

Official Full Name carbonyl reductase 3
Background Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols.The enzyme is classified as a monomeric NADPH-dependent oxidoreductase.CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
Synonyms CBR3; carbonyl reductase 3; carbonyl reductase [NADPH] 3; SDR21C2; short chain dehydrogenase/reductase family 21C; member 2; Carbonyl reductase (NADPH) 3; Carbonyl reductase (NADPH) 3 EC 1.1.1.184; CBR 3; CBR3_HUMAN; EC 1.1.1.184; hCBR3; NADPH dependent carbonyl reductase 3; NADPH-dependent carbonyl reductase 3; Short chain dehydrogenase/reductase family 21C member 2; OTTHUMP00000109012; short chain dehydrogenase/reductase family 21C, member 2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CBR3-0468H Recombinant Human CBR3 Protein, GST-Tagged Wheat Germ GST
    Human CBR3-10763H Recombinant Human CBR3, GST-tagged E.coli GST
    Human CBR3-184H Recombinant Human Carbonyl Reductase 3, His-tagged E.coli His
    Human CBR3-185H Recombinant Human CBR3, MYC/DDK-tagged HEK293 Myc/DDK
    Human CBR3-199H Recombinant Human CBR3, His tagged E.coli N/A
    Human CBR3-26328TH Recombinant Human CBR3, His-tagged E.coli His
    Human CBR3-7810HCL Recombinant Human CBR3 293 Cell Lysate HEK293 N/A
    Mouse CBR3-2788M Recombinant Mouse CBR3 Protein Mammalian Cell His
    Mouse Cbr3-440M Recombinant Mouse Cbr3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rhesus Macaque CBR3-644R Recombinant Rhesus monkey CBR3 Protein, His-tagged Mammalian Cell His

    cbr3 involved in several pathways and played different roles in them. We selected most pathways cbr3 participated on our site, such as Arachidonic acid metabolism, Metabolism of xenobiotics by cytochrome P, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with cbr3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism PLA2G4A; CYP4F2; PTGS2A; CYP1A2; PTGES2; AWAT2; GGT1A; PLA2G1B; PTGES3B; GPX8
    Metabolism of xenobiotics by cytochrome P UGT1AB; UGT1A6; MGST1.2; DHDHL; UGT2B7; UGT5G1; DHDH; UGT2A1; GSTA2; CYP1A
    Metabolic pathways PYGL; ALLC; ATP6V0D1; Cel; G6PCA.2; PNLIPRP2; MAT2AA; NDUFS1; PPCDC; GGPS1

    cbr3 has several biochemical functions, for example, 3-keto sterol reductase activity, NADPH binding, carbonyl reductase (NADPH) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cbr3 itself. We selected most functions cbr3 had, and list some proteins which have the same functions with cbr3. You can find most of the proteins on our site.

    Function Related Protein
    3-keto sterol reductase activity CBR3; DHRS4; HSD17B7
    NADPH binding HMGCR; QDPR; CRYZ; DECR1; CBR4; MTRR; CBR3; GRHPR; KCNAB1; TP53I3
    carbonyl reductase (NADPH) activity CBR2; DHRS4; CBR3; CBR1; DHRS2

    cbr3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cbr3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cbr3.

    SGK1; USP3; ARIH2; RAB35; GABARAP; LDLR; CBR1; MKI67; RPS10; CCNL2; GABARAPL1

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