CCNC

  • Official Full Name

    cyclin C

  • Overview

    The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    CCNC;cyclin C;cyclin-C;CycC;CCNC_HUMAN;hSRB11;OTTHUMP00000016897;SRB11 homolog

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
CCNC-10859H Recombinant Human CCNC, His-tagged E.coli Human His 1-283a.a.
CCNC-27518TH Recombinant Human CCNC, His-tagged E.coli Human His Full L.
CCNC-0657H Recombinant Human CCNC Protein, GST-Tagged Wheat Germ Human GST
CCNC-07H Recombinant Human Cyclin C E.coli Human Non 120-303 a.a.
CCNC-10317Z Recombinant Zebrafish CCNC Mammalian Cells Zebrafish His
CCNC-4033C Recombinant Chicken CCNC Mammalian Cells Chicken His
CCNC-823H Recombinant Human CCNC Protein, GST-His-tagged E.coli Human GST&His
CCNC-7714HCL Recombinant Human CCNC 293 Cell Lysate HEK293 Human Non
CCNC-7715HCL Recombinant Human CCNC 293 Cell Lysate HEK293 Human Non
CCNC-2965HF Recombinant Full Length Human CCNC Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 283 amino acids

    Involved Pathway

    CCNC involved in several pathways and played different roles in them. We selected most pathways CCNC participated on our site, such as Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,Constitutive Signaling by NOTCH1 PEST Domain Mutants,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Disease LRRFIP1,EPM2A,DPF1,OPN1LW,AP2M1,VPS37A,TLR6,PPIA,CTBP2,CTBP1
    Gene Expression ALKBH8,ZFP37,PAPOLA,ZNF484,NR1D2,DDX4,EFCAB11,MED20,TACO1,TXN
    Fatty acid, triacylglycerol, and ketone body metabolism GLIPR1,G0S2,PLIN2,Agmo,CPT2,SLC25A1,DGAT1B,SLC25A20,CDK8,ACOT9.1
    Constitutive Signaling by NOTCH1 PEST Domain Mutants MIB1,JAG2,CDK8,ADAM10,HDAC6,HEYL,HEY2,JAG1,HEY1,HDAC5
    Generic Transcription Pathway ZNF215,ZNF354A,CCNT2A,ZNF556,COX6C,TRIM28,ZNF486,ZNF614,NR2C2AP,ZNF543
    Developmental Biology MED31,TRPC4,DPYSL2B,NR6A1,EBF1,DPYSL3,CFC1,KIF4A,DUSP4,LGI2A
    Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants HEYL,JAG2,CDK8,HEY2,JAG1,HEY1,HDAC5,HDAC6,ADAM10,MIB1
    Diseases of signal transduction MIB1,CPSF6,RLBP1,HDAC5,KREMEN1,TRAT1,KREMEN2,STRA6,TNKS2,CTBP2

    Protein Function

    CCNC has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase regulator activity,protein binding,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNC itself. We selected most functions CCNC had, and list some proteins which have the same functions with CCNC. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase activity RNF149,HECW1,C12orf51,CBL,HERC4,RNF217,RNF152,TRIM3,FBXL22,RNF14
    protein binding TP73,C19orf60,SEPT5,HTRA2,AMBP,NRSN1,PSMA2,ABCD2,IL17F,DTX2
    cyclin-dependent protein serine/threonine kinase regulator activity CCNL1A,CCNT2B,CCNT2A,PSTPIP2,CKS2,CCNE1,CCNT2,CCNY,CCNL1B,CCNL1

    Interacting Protein

    CCNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNC here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNC.

    CDK8

    Resources

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