ccr5
Share
  • Official Full Name
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • Background
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms
  • CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene); CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5; C-C chemokine receptor type 5; chemr13; HIV-1 fusion coreceptor; chemokine receptor CCR5; C-C motif chemokine receptor 5 A159A;
Cat.#:CCR5-0693HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR5 Protein
+Inquiry
Cat.#:CCR5-10886HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCR5, GST-tagged
+Inquiry
Cat.#:CCR5-120HTag:GST
Source (Host):Species:Human
Product nameRecombinant Human CCR5, GST-tagged
+Inquiry
Cat.#:CCR5-366HTag:N/A
Source (Host):Species:Human
Product nameHuman CCR5 peptide
+Inquiry
Cat.#:CCR5-3016MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CCR5 Protein
+Inquiry
Cat.#:CCR5-1229RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CCR5 Protein
+Inquiry
Cat.#:CCR5-708RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCR5 Protein, His-tagged
+Inquiry
Cat.#:CCR5-4659CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCR5
+Inquiry
Cat.#:CCR5-309HCLTag:Flag
Source (Host):HEK293TSpecies:Human
Product nameRecombinant Human CCR5 cell lysate
+Inquiry
Cat.#:Kit-1048Tag:
Source (Host):Species:
Product nameNAD+/NADH Colorimetric Assay Kit (384-well)
+Inquiry
Cat.#:Kit-1153Tag:
Source (Host):Species:
Product nameCCR5 CHO-K1 β-Arrestin GPCR Assay Kit
+Inquiry
Cat.#:Kit-1154Tag:
Source (Host):Species:
Product nameCCR5 Activated GPCR Internalization Assay Kit
+Inquiry
Cat.#:Kit-1155Tag:
Source (Host):Species:
Product namecAMP CCR5 CHO-K1 GPCR Assay Kit
+Inquiry
Cat.#:Kit-0889Tag:
Source (Host):Species:
Product nameHydroxyl Free Radical Assay Kit
+Inquiry
Cat.#:CSC-RG0042Tag:
Source (Host):Species:Human
Product nameHuman CCR5-SNAP Stable Cell Line-HEK293
+Inquiry
Cat.#:CSC-RG0203Tag:
Source (Host):Species:Human
Product nameHuman CCR5-FLAG Stable Cell Line-HEK293T
+Inquiry
Cat.#:CSC-RG0491Tag:
Source (Host):Species:Human
Product nameHuman CCR5/Gi Stable Cell Line-HEK293
+Inquiry
Cat.#:CSC-RG0492Tag:
Source (Host):Species:Human
Product nameHuman CCR5/Gi Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-RG0824Tag:
Source (Host):Species:Human
Product nameHuman CCR5 Stable Cell Line-HEK293-CNG
+Inquiry
Cat.#:CSC-RG0632Tag:
Source (Host):Species:Monkey
Product nameMonkey CCR5/Galpha15 Stable Cell Line-Chem-1
+Inquiry
Cat.#:CSC-P0590Tag:
Source (Host):Species:Human
Product nameAnti-Human CCR5 MAb Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-P0591Tag:
Source (Host):Species:Human
Product nameAnti-Human CCR5 F(ab) Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-P0592Tag:
Source (Host):Species:Human
Product nameAnti-Human CCR5 scFv Stable Cell Line-CHO
+Inquiry

CCR5 Related Articles

Gardner, MR; Kattenhorn, LM; et al. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. NATURE 519:87-U173(2015).
Yi, HA; Diaz-Rohrer, B; et al. The Membrane Proximal External Regions of gp41 from HIV-1 Strains HXB2 and JRFL Have Different Sensitivities to Alanine Mutation. BIOCHEMISTRY 54:1681-1693(2015).

CCR5 Related Gene Family

Chemokines Cytokines