Recombinant Human CCR5 protein, Flag & His-tagged

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Recombinant Human CCR5 protein, Flag & His-tagged

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Cat.No. : CCR5-681H
Product Overview : Human CCR5, Flag,His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 2 - Arg 223 & Glu 227 - Arg 319 (Accession # P51681-1(C58Y,G163N,A233D,K303E)).
Description : Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Source : HEK293
Species : Human
Tag : Flag & His
Predicted N Terminal : Asp
Form : Delivered as bulk protein in a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with Glycerol as protectant.
Molecular Mass : The protein has a calculated MW of 46.0 kDa. The protein migrates as 33-35 kDa and 40-45 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Protein length : Asp 2 - Arg 223 & Glu 227 - Arg 319
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >85% as determined by SDS-PAGE.
Storage : Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : This product is supplied as sterile liquid solution and shipped frozen with dry ice, please inquire the shipping cost.
SDS-PAGE of CCR5-681H :

Bioactivity-ELISA of CCR5-681H :

Gene Name : CCR5 C-C motif chemokine receptor 5 [ Homo sapiens (human) ]
Official Symbol : CCR5
Synonyms : CCR5; CMKBR5; CD195; CC-CKR-5; CHEMR13
Gene ID : 1234
mRNA Refseq : NM_000579.4
Protein Refseq : NP_000570.1
MIM : 601373
UniProt ID : P51681
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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