CD248

  • Official Full Name

    CD248 molecule, endosialin

  • Overview

    Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
  • Synonyms

    CD248; CD248 molecule, endosialin; TEM1; CD164L1; endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; tumor endothelial marker 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Rhesus monkey
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • hIgG1
  • hIgG4
  • His (Fc)
  • Avi
  • N/A
  • N
  • SUMO
  • Strep
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD248-23H Active Recombinant Human CD248 Protein, His-tagged Mammalian cells His Gln18-Arg685
Human CD248-10932H Recombinant Human CD248, GST-tagged E.coli GST 399-687a.a.
Human CD248-0758H Recombinant Human CD248 Protein, GST-Tagged Wheat Germ GST
Human CD248-315HCL Recombinant Human CD248 cell lysate N/A
Human CD248-3089HF Recombinant Full Length Human CD248 Protein, GST-tagged In Vitro Cell Free System GST 757 amino acids
Human CD248-230H Recombinant Human CD248 protein, His-tagged E.coli His 21-401 aa
Human CD248-3581H Recombinant Human CD248 Protein (Gly30-Cys156), C-His tagged E.coli C-His Gly30-Cys156
Human CD248-5033H Recombinant Human CD248 Protein (Met1-Leu687), C-His tagged Mammalian cells C-His Met1-Leu687
Human CD248-2630H Recombinant Human CD248 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD248-1111H Recombinant Human CD248 Protein (Gln18-Glu245), N-His tagged E.coli N-His Gln18-Glu245
Human CD248-2630H-B Recombinant Human CD248 Protein Pre-coupled Magnetic Beads HEK293
Mouse CD248-3063M Recombinant Mouse CD248 Protein Mammalian Cell His
Mouse CD248-1447M-B Recombinant Mouse CD248 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd248-01M Recombinant Mouse Cd248 Protein, His-tagged, Biotinylated HEK293 His
Mouse CD248-1447M Recombinant Mouse CD248 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cd248-5480M Recombinant Mouse Cd248 Protein (Val19-Cys156), SUMO and Strep tagged E.coli SUMO and Strep Val19-Cys156
Rhesus monkey CD248-1630R Recombinant Rhesus Monkey CD248 Protein, hIgG4-tagged HEK293 hIgG4
Rhesus monkey CD248-1628R Recombinant Rhesus Monkey CD248 Protein HEK293 N/A
Rhesus monkey CD248-1629R Recombinant Rhesus Monkey CD248 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus Macaque CD248-731R Recombinant Rhesus monkey CD248 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD248-557R-B Recombinant Rhesus Macaque CD248 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CD248-557R Recombinant Rhesus Macaque CD248 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD248 involved in several pathways and played different roles in them. We selected most pathways CD248 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CD248 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CD248 has several biochemical functions, for example, calcium ion binding, carbohydrate binding, extracellular matrix binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD248 itself. We selected most functions CD248 had, and list some proteins which have the same functions with CD248. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingACTN4;GSNA;CRB2A;CCDC48;GRM7;NKD1;PLA2G5;CAPNS1B;PSPH
carbohydrate bindingMGAT2;ILLR1;VCAN;BCAN;GALNTL2;LGALS9L1;NOMO3;CLEC1A;KLRC1
extracellular matrix bindingBGN;TGFBI;ITGB3;ITGAV;SID4;VEGFA;GPR56;CD248;ITGA2B
molecular_functionAAMDC;CCDC75;RHOX3E;D16ERTD472E;SMG8;TMEM9;RPS4Y2;TAS2R110;FHOD3

CD248 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD248 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD248.

TFAP2C

Research Area

Related articles

Li, CS; Wang, JY; et al. Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer. ONCOTARGET 5:6994-7012(2014).
Li, CS; Chacko, AM; et al. Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model. CANCER BIOLOGY & THERAPY 15:443-451(2014).
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