CD2BP2

  • Official Full Name

    CD2 (cytoplasmic tail) binding protein 2

  • Overview

    This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
  • Synonyms

    CD2BP2; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; LIN1; PPP1R59; protein phosphatase 1; regulatory subunit 59; Snu40; FWP010; U5 snRNP 52K protein; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5-52K;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD2BP2-0775H Recombinant Human CD2BP2 Protein, GST-Tagged Wheat Germ GST
Human CD2BP2-175HCL Recombinant Human CD2BP2 lysate HEK293 N/A
Human CD2BP2-3097HF Recombinant Full Length Human CD2BP2 Protein, GST-tagged In Vitro Cell Free System GST 341 amino acids
Mouse CD2BP2-3070M Recombinant Mouse CD2BP2 Protein Mammalian Cell His
Mouse CD2BP2-1450M Recombinant Mouse CD2BP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CD2BP2-1450M-B Recombinant Mouse CD2BP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CD2BP2-735R Recombinant Rhesus monkey CD2BP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD2BP2-561R Recombinant Rhesus Macaque CD2BP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD2BP2-561R-B Recombinant Rhesus Macaque CD2BP2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CD2BP2-11196Z Recombinant Zebrafish CD2BP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CD2BP2 involved in several pathways and played different roles in them. We selected most pathways CD2BP2 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD2BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionZKSCAN4;NR1D2;HNRNPL2;ZNF34;ZBTB8OS;ZNF79;ZNF426;ZNF738;ZFP37
Processing of Capped Intron-Containing Pre-mRNAHNRNPF;PRPF8;HNRNPH2;PTBP1;HNRNPA0B;HNRNPH1;RNPC3;CSTF3;HNRNPUL1
mRNA SplicingHNRNPF;PTBP1A;PDCD7;HNRNPA0L;SFRS3A;HNRNPH2;SNRNP25;HNRNPL2;PRPF8
mRNA Splicing - Major PathwayHNRPL;HNRNPH1;SUGP1;CCAR1;PTBP1;SFRS3A;HNRNPA0B;DNAJC8;BCAS2
mRNA processingWBP4;ZFP622;EBI3;PSKH1;HNRNPH2;ZFML;HNRPL;OASL2;DHX8

CD2BP2 has several biochemical functions, for example, protein binding, ribonucleoprotein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD2BP2 itself. We selected most functions CD2BP2 had, and list some proteins which have the same functions with CD2BP2. You can find most of the proteins on our site.

Function Related Protein
protein bindingSCRT1;CBX6;PWWP2B;SLC9A3;SUV39H1;RBM23;CDC5L;ULK2;FBXO28
ribonucleoprotein complex bindingSECISBP2;RNASEL;PRPF31;PQBP1;RNF135;YBX2;ITCH;WDR12;PITX2

CD2BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD2BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD2BP2.

CD2; PRPF6

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