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Official Full Name cell division cycle 25 homolog B
Background cdc25 is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while pho
Synonyms CDC25B; cell division cycle 25 homolog B (S. pombe); cell division cycle 25 homolog B (S. cerevisiae) , cell division cycle 25B; M-phase inducer phosphatase 2; cell division cycle 25B; dual specificity phosphatase Cdc25B
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Met
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC25B-0916H Recombinant Human CDC25B Protein, GST-Tagged Wheat Germ GST
    Human CDC25B-11000H Recombinant Human CDC25B, His-tagged E.coli His
    Human CDC25B-1512H Recombinant Human CDC25B (Active), GST-tagged Sf9 Insect Cell GST
    Human CDC25B-547H Recombinant Human CDC25B Protein, Met & His-tagged E.coli Met/His
    Human CDC25B-7665HCL Recombinant Human CDC25B 293 Cell Lysate HEK293 N/A
    Human CDC25B-7666HCL Recombinant Human CDC25B 293 Cell Lysate HEK293 N/A
    Rat CDC25B-1272R Recombinant Rat CDC25B Protein Mammalian Cell His
    Zebrafish CDC25B-6535Z Recombinant Zebrafish CDC25B Mammalian Cell His

    cdc25b involved in several pathways and played different roles in them. We selected most pathways cdc25b participated on our site, such as MAPK signaling pathway, Cell cycle, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdc25b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RASGRP3; MAPK10; NGF; IKBKG; NTF3; IL1R2; FLNB; GADD45AB; RELA; RPS6KA3B
    Cell cycle SUN1; TGFB3; CSNK2A1; E2F4; FGFR1OP; HIST3H2BB; MYC; NUP35; CDK4; RUVBL2
    Progesterone-mediated oocyte maturation CCNA2; GNAI1; PRKACBA; CPEB1; PRKACA; PIK3CA; CDC25B; CDC16; CDH1-A; RPS6KA6
    MicroRNAs in cancer CDCA5; HMGA2; SOS1; TP63; MCL1; EFNA3; ZFPM2; ST14; PTEN; BCL2L2

    cdc25b has several biochemical functions, for example, protein binding, protein kinase binding, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cdc25b itself. We selected most functions cdc25b had, and list some proteins which have the same functions with cdc25b. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SHC4; SMC3; DNAI1; COL6A5; GDAP2; GSDMD; ITSN1; LRRK1; EPM2A; BAG3
    protein kinase binding RACGAP1; FBXW5; MAML1; BAG5; TCF7L2; DCX; CDH2; SMAD3; TP73; MAPK4
    protein tyrosine phosphatase activity PTPRU; MTMR7B; DUSP11; PTPRFB; PTPN6; DUSP3; PTPRUB; PTPRJ; PTPREB; PTPN14

    cdc25b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdc25b here. Most of them are supplied by our site. Hope this information will be useful for your research of cdc25b.


    Lee, KH; Tsutsui, T; et al. Overexpression of mutant cell division cycle 25 homolog B (CDC25B) enhances the efficiency of selection in Chinese hamster ovary cells. CYTOTECHNOLOGY 65:1017-1026(2013).
    Kang, H; Hwang, SC; et al. Cdc25B phosphatase participates in maintaining metaphase II arrest in mouse oocytes. MOLECULES AND CELLS 35:514-518(2013).

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