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Official Full Name CDC42 binding protein kinase alpha (DMPK-like)
Background The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Synonyms CDC42BPA; CDC42 binding protein kinase alpha (DMPK-like); CDC42 binding protein kinase alpha (DMPK like); serine/threonine-protein kinase MRCK alpha; FLJ23347; KIAA0451; MRCK; MRCKA; PK428; DKFZp686P1738; MGC189823; A930014J19Rik; CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha dmpk like; CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; DKFZp686L1738; DMPK like; DMPK-like alpha; MRCK alpha; MRCKA_HUMAN; Myotonic dystrophy kinase related CDC42 binding protein kinase alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; Myotonic dystrophy protein kinase-like alpha; OTTHUMP00000035727; OTTHUMP00000035728; OTTHUMP00000035729; OTTHUMP00000035730; RP5-1087E8.4; Ser thr protein kinase PK428; Ser thr protein kinase related to the myotonic dystrophy protein kinase; Serine/threonine protein kinase MRCK alpha; ser-thr protein kinase PK428; CDC42 binidng protein kinase beta; C
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC42BPA-0938H Recombinant Human CDC42BPA Protein, GST-Tagged Insect Cell GST
    Human CDC42BPA-0939H Recombinant Human CDC42BPA Protein, GST-Tagged Wheat Germ GST
    Human CDC42BPA-26225TH Recombinant Human CDC42BPA N/A
    Human CDC42BPA-357H Recombinant Human CDC42BPA, GST-tagged, Active Sf9 Insect Cell GST
    Human CDC42BPA-368H Recombinant Human CDC42 Binding Protein Kinase Alpha (DMPK-like), His-tagged Insect Cell His
    Human CDC42BPA-7654HCL Recombinant Human CDC42BPA 293 Cell Lysate HEK293 N/A
    Rat CDC42BPA-1278R Recombinant Rat CDC42BPA Protein Mammalian Cell His
    Chicken CDC42BPA-4309C Recombinant Chicken CDC42BPA Mammalian Cell His

    cdc42bpa involved in several pathways and played different roles in them. We selected most pathways cdc42bpa participated on our site, such as CDC42 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdc42bpa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    CDC42 signaling events BAIAP2; ACTR3; ACTR2; ARPC2; CTNNA1; CFL1; EPS8; ARPC5; ARPC4; IQGAP3

    cdc42bpa has several biochemical functions, for example, ATP binding, identical protein binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdc42bpa itself. We selected most functions cdc42bpa had, and list some proteins which have the same functions with cdc42bpa. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding NFKB1; PARK2; HACL1; ABCD1; PARK7; GRB2; HSP90AA1; GPSM2; SLC2A1; C1QL2
    magnesium ion binding MARK2; PRPS1A; PDXK; ADPRHL1; NIM1K; ENOPH1; OPA1; PKMB; TSSK2; HPRT1L
    protein binding DOCK4; PSMB1; ATXN7; PPARG; AKAP7; SLC25A10; NR2F6; BOLA1; ATP6V1D; STX2
    protein serine/threonine kinase activity RAF1B; SRPK2; SMOK2B; DMPK; TRIOA; MAP4K3; CAMK2D2; SIK3; MAPK1; PLK3

    cdc42bpa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdc42bpa here. Most of them are supplied by our site. Hope this information will be useful for your research of cdc42bpa.

    CDC42; MYL12A; RHOQ; o92972-pro_0000278742; SNAPIN; TAF1; CDC42BPB

    Hu, ZB; Li, Z; et al. Association analysis identifies new risk loci for non-obstructive azoospermia in Chinese men. NATURE COMMUNICATIONS 5:-(2014).
    Balasenthil, S; Chen, NY; et al. A Migration Signature and Plasma Biomarker Panel for Pancreatic Adenocarcinoma. CANCER PREVENTION RESEARCH 4:137-149(2011).

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