Recombinant Human CDH12 Protein, GST-Tagged CDH12-0973H

Recombinant Human CDH12 Protein, GST-Tagged

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Recombinant Human CDH12 Protein, GST-Tagged

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Cat.No. : CDH12-0973H
Product Overview : Human CDH12 full-length ORF (NP_004052.2, 1 a.a. - 794 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 114.7 kDa
AA Sequence : MLTRNCLSLLLWVLF DGGLLTPLQPQPQQT LATEPRENVIHLPGQ RSHFQRVKRGWVWNQ FFVLEEYVGSEPQYV GKLHSDLDKGEGTVK YTLSGDGAGTVFTID ETTGDIHAIRSLDRE EKPFYTLRAQAVDIE TRKPLEPESEFIIKV QDINDNEPKFLDGPY VATVPEMSPVGAYVL QVKATDADDPTYGNS ARVVYSILQGQPYFS IDPKTGVIRTALPNM DREVKEQYQVLIQAK DMGGQLGGLAGTTIV NITLTDVNDNPPRFP KSIFHLKVPESSPIG SAIGRIRAVDPDFGQ NAEIEYNIVPGDGGN LFDIVTDEDTQEGVI KLKKPLDFETKKAYT FKVEASNLHLDHRFH SAGPFKDTATVKISV LDVDEPPVFSKPLYT MEVYEDTPVGTIIGA VTAQDLDVGSSAVRY FIDWKSDGDSYFTID GNEGTIATNELLDRE STAQYNFSIIASKVS NPLLTSKVNILINVL DVNEFPPEISVPYET AVCENAKPGQIIQIV SAADRDLSPAGQQFS FRLSPEAAIKPNFTV RDFRNNTAGIETRRN GYSRRQQELYFLPVV IEDSSYPVQSSTNTM TIRVCRCDSDGTILS CNVEAIFLPVGLSTG ALIAILLCIVILLAI VVLYVALRRQKKKDT LMTSKEDIRDNVIHY DDEGGGEEDTQAFDI GALRNPKVIEENKIR RDIKPDSLCLPRQRP PMEDNTDIRDFIHQR LQENDVDPTAPPYDS LATYAYEGSGSVAES LSSIDSLTTEADQDY DYLTDWGPRFKVLAD MFGEEESYNPDKVT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CDH12 cadherin 12, type 2 (N-cadherin 2) [ Homo sapiens ]
Official Symbol : CDH12
Synonyms : CDH12; cadherin 12, type 2 (N-cadherin 2); cadherin-12; Br cadherin; CDHB; Br-cadherin; N-cadherin 2; brain cadherin; brain-cadherin; neuronal cadherin 2; neural type cadherin 2; cadherin, neural type, 2; FLJ34857;
Gene ID : 1010
mRNA Refseq : NM_004061
Protein Refseq : NP_004052
MIM : 600562
UniProt ID : P55289

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