CHD8

  • Official Full Name

    chromodomain helicase DNA binding protein 8

  • Overview

    CHD8 belongs to the chromodomain helicase DNA-binding (CHD) family of ATP-dependent chromatin remodeling proteins. The CHD family of proteins has been shown to play an important role in regulating gene expression by utilizing the energy derived from ATP h

  • Synonyms

    CHD8;chromodomain helicase DNA binding protein 8;helicase with SNF2 domain 1 , HELSNF1;chromodomain-helicase-DNA-binding protein 8;DUPLIN;KIAA1564;axis duplication inhibitor;ATP-dependent helicase CHD8;helicase with SNF2 domain 1;HELSNF1

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • Zebrafish
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • E.coli
  • GST
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHD8-1217H Recombinant Human CHD8 Protein, GST-Tagged Wheat Germ Human GST
CHD8-1366R Recombinant Rat CHD8 Protein Mammalian Cells Rat His
CHD8-3383M Recombinant Mouse CHD8 Protein Mammalian Cells Mouse His
CHD8-7974Z Recombinant Zebrafish CHD8 Mammalian Cells Zebrafish His
CHD8-1024R Recombinant Rat CHD8 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
CHD8-1024R-B Recombinant Rat CHD8 Protein Pre-coupled Magnetic Beads HEK293 Rat
CHD8-1635M Recombinant Mouse CHD8 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CHD8-1635M-B Recombinant Mouse CHD8 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CHD8-773H Recombinant Human CHD8 Protein, His-tagged E.coli Human His Leu823-Arg1288

    Involved Pathway

    CHD8 involved in several pathways and played different roles in them. We selected most pathways CHD8 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway PPP3R1B,CER1,SERPINF1,LRP6,FZD3B,LEF1,FZD8B,WNT2BA,PPARD,CCND2

    Protein Function

    CHD8 has several biochemical functions, for example, ATP binding,DNA binding,DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD8 itself. We selected most functions CHD8 had, and list some proteins which have the same functions with CHD8. You can find most of the proteins on our site.

    Function Related Protein
    histone binding HIST1H4D,CD1D,PHF21B,PIH1D1,L3MBTL2,PHF21A,RBBP4,HIST1H47,CHAF1B,USP49
    DNA-dependent ATPase activity SMARCA4,SMARCA2,RAD51L3,MSH4,XRCC3,DMC1,MSH6,MSH3,MSH2,ERCC6
    protein binding MASP1,RNF24,SCNN1G,ATP2C2,CACNA2D1A,TMEM123,FADD,KLRC2,MRPS12,DUSP7
    DNA binding TOP1,OTX1A,HOXB10A,ZBTB3,MTF2,ZNF512,BHLHE22,MAFGA,ZFP768,HMG20A
    beta-catenin binding LZIC,AXIN2,PTPRK,SHROOM2,VCL,TCF7L1A,KLF4,TCF7,SLC9A3R2,PXN
    armadillo repeat domain binding TCF7L2,CTNNBIP1,STRN4,CALCOCO1,LEF1,CNOT1,STRN,AXIN2,AXIN1
    hydrolase activity, acting on acid anhydrides SMARCA4A,CHD9
    ATP binding DNAHC8,ALK,CHTF18,ATP1A1B,RENBP,KATNA1,TCP1,CDC42BPA,Acsm2a,GRK5
    hydrolase activity ABHD17B,PPM1DA,MCPT9,Acr,EGFBP2,DNASE2A,PNPLA5,ABHD2A,PNPLA8,G6PC3

    Interacting Protein

    CHD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD8.

    Ctcf

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