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CHD8

  • Official Full Name

    chromodomain helicase DNA binding protein 8

  • Overview

    CHD8 belongs to the chromodomain helicase DNA-binding (CHD) family of ATP-dependent chromatin remodeling proteins. The CHD family of proteins has been shown to play an important role in regulating gene expression by utilizing the energy derived from ATP h
  • Synonyms

    CHD8; chromodomain helicase DNA binding protein 8; helicase with SNF2 domain 1 , HELSNF1; chromodomain-helicase-DNA-binding protein 8; DUPLIN; KIAA1564; axis duplication inhibitor; ATP-dependent helicase CHD8; helicase with SNF2 domain 1; HELSNF1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHD8-1217H Recombinant Human CHD8 Protein, GST-Tagged Wheat Germ GST
Human CHD8-773H Recombinant Human CHD8 Protein, His-tagged E.coli N-His Leu823-Arg1288
Mouse CHD8-3383M Recombinant Mouse CHD8 Protein Mammalian Cell His
Mouse CHD8-1635M Recombinant Mouse CHD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CHD8-1635M-B Recombinant Mouse CHD8 Protein Pre-coupled Magnetic Beads HEK293
Rat CHD8-1366R Recombinant Rat CHD8 Protein Mammalian Cell His
Rat CHD8-1024R Recombinant Rat CHD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CHD8-1024R-B Recombinant Rat CHD8 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CHD8-7974Z Recombinant Zebrafish CHD8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHD8 involved in several pathways and played different roles in them. We selected most pathways CHD8 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayTRP53;FZD2;WIF1;PRKCBA;PPP3CA;PRKACBB;NFATC2;PLCB4;FZD1

CHD8 has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD8 itself. We selected most functions CHD8 had, and list some proteins which have the same functions with CHD8. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSLFNL1;GALK2;INSRR;TOR2A;EPHA2A;ABCA4;ABCG1;SNRNP200;RET
DNA bindingZNF227;NEUROD6A;CHD9;LCOR;HOXB2A;POLG2;NUP153;MEIS2A;NPAS2
DNA helicase activityDNA2;RAD54B;RECQL5;MCM5;PEO1;WRN;RUVBL2;RUVBL1;PIF1
DNA-dependent ATPase activityDHX36;MSH3;RAD51L1;SMARCA2;TTF2;CDK7;IGHMBP2;DMC1;MSH4
armadillo repeat domain bindingSTRN;CALCOCO1;TCF7L2;AXIN1;LEF1;AXIN2;CHD8;STRN4;CNOT1
beta-catenin bindingCDH2;MED12;APC;BTRC;DACT3;ASH2L;TCF7L1A;DVL3;FAM123B
chromatin bindingPOU2F1;LOXL2;HDAC7;UBTFL;CREBBP;NONO;TCF7L1A;CENPB;HDAC2
helicase activityDHX32A;DHX37;SMARCA2;BLM;DHX33;EIF4A1;CHD9;FANCM;HELLS
histone bindingPRKCBB;COPRS;PIH1D1;AIRE;DAXX;RNF20;ASF1B;APBB1;PYGO2
hydrolase activityATP9B;ACY3.1;PNPLA5;ACOT5;FAAH2;MMP30;PLA2G4AA;ATP13A3;RAD9
hydrolase activity, acting on acid anhydridesCHD8;CHD9;SMARCA4A
methylated histone bindingKAT8;MPHOSPH8;RRP8;WDR92;SPIN1;CBX4;UHRF1;MSH6;ZMYND11
nucleotide bindingCSNK1DB;GDPGP1;MAPK8A;TRIO;POLDIP3;BSK146;NXF3;RAB3DA;HRASB
p53 bindingRNF20;EP300;SETD8;MSX1;DAXX;ZMAT4;NUAK1;ZNF346;TRP63
protein bindingCARD8;ASMTL;ADAMTS13;UBE2K;FGA;Mill2;CDK5R1;Il4ra;FIG4

CHD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD8.

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