• Official Full Name

    carbohydrate (chondroitin 4) sulfotransferase 12

  • Background

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5 UTRs have been found for this gene.
  • Synonyms

    CHST12; carbohydrate (chondroitin 4) sulfotransferase 12; carbohydrate sulfotransferase 12; C4S 2; C4ST2; C4S2; C4ST 2; Chondroitin 4 O sulfotransferase 2; Chondroitin 4 sulfotransferase 2; Sulfotransferase Hlo; chondroitin 4-sulfotransferase 2; chondroitin 4-O-sulfotransferase 2; C4S-2; C4ST-2;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Price
    Human CHST12-1296H Recombinant Human CHST12 Protein, GST-Tagged Wheat Germ GST
    Human CHST12-11225H Recombinant Human CHST12, His-tagged E.coli His
    Human CHST12-7507HCL Recombinant Human CHST12 293 Cell Lysate HEK293 N/A
    Human CHST12-3251HF Recombinant Full Length Human CHST12 Protein, GST-tagged In Vitro Cell Free System GST
    Mouse CHST12-3447M Recombinant Mouse CHST12 Protein Mammalian Cell His
    Mouse CHST12-1672M Recombinant Mouse CHST12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Chst12-2159M Recombinant Mouse Chst12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse CHST12-1672M-B Recombinant Mouse CHST12 Protein Pre-coupled Magnetic Beads HEK293
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    CHST12 involved in several pathways and played different roles in them. We selected most pathways CHST12 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateCHST11;CHST3;CHST15;CHST12;CHSY3;CHST14;B4GALT7;B3GALT6;B3GAT3

    CHST12 has several biochemical functions, for example, 3-phosphoadenosine 5-phosphosulfate binding, chondroitin 4-sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST12 itself. We selected most functions CHST12 had, and list some proteins which have the same functions with CHST12. You can find most of the proteins on our site.

    Function Related Protein
    3-phosphoadenosine 5-phosphosulfate bindingGAL3ST4;HS3ST5;ENPP1;CHST15;CHST12
    chondroitin 4-sulfotransferase activityCHST12;CHST11

    CHST12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST12 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST12.

    UGGT1; Gspt1; Mzt2; CBX8

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