Recombinant Human CHST12 Protein, GST-Tagged

• Cat.No.: CHST12-1296H
• Product Overview: Human CHST12 full-length ORF (AAH02918, 1 a.a. - 414 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 71.28 kDa
• AA Sequence: MTKARLFRLWLVLGSVFMILLIIVY WDSAGAAHFYLHTSFSRPHTGPPLP TPGPDRDRELTADSDVDEFLDKFLS AGVKQSDLPRKETEQPPAPGSMEES VRGYDWSPRDARRSPDQGRQQAERR SVLRGFCANSSLAFPTKERAFDDIP NSELSHLIVDDRHGAIYCYVPKVAC TNWKRVMIVLSGSLLHRGAPYRDPL RIPREHVHNASAHLTFNKFWRRYGK LSRHLMKVKLKKYTKFLFVRDPFVR LISAFRSKFELENEEFYRKFAVPML RLYANHTSLPASAREAFRAGLKVSF ANFIQYLLDPHTEKLAPFNEHWRQV YRLCHPCQIDYDFVGKLETLDEDAA QLLQLLQVDRQLRFPPSYRNRTASS WEEDWFAKIPLAWRQQLYKLYEADF VLFGYPKPENLLRD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 [ Homo sapiens ]
• Official Symbol: CHST12
• Synonyms: CHST12; carbohydrate (chondroitin 4) sulfotransferase 12; carbohydrate sulfotransferase 12; C4S 2; C4ST2; sulfotransferase Hlo; chondroitin 4-sulfotransferase 2; chondroitin 4-O-sulfotransferase 2; C4S-2; C4ST-2
• Gene ID: 55501
• mRNA Refseq: NM_001243794
• Protein Refseq: NP_001230723
• MIM: 610129
• UniProt ID: Q9NRB3