Recombinant Full Length Human CLDN19 Protein, GST-tagged

• Cat.No.: CLDN19-2048HF
• Product Overview: Human CLDN19 full-length ORF ( AAH30524, 1 a.a. - 211 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 48.95 kDa
• Protein Length: 211 amino acids
• AA Sequence: MANSGLQLLGYFLALGGWVGIIAST ALPQWKQSSYAGDAIITAVGLYEGL WMSCASQSTGQVQCKLYDSLLALDG HIQSARALMVVAVLLGFVAMVLSVV GMKCTRVGDSNPIAKGRVAIAGGAL FILAGLCTLTAVSWYATLVTQEFFN PSTPVNARYEFGPALFVGWASAGLA VLGGSFLCCTCPEPERPNSSPQPYR PGPSAAAREYV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLDN19 claudin 19 [ Homo sapiens ]
• Official Symbol: CLDN19
• Synonyms: CLDN19; claudin 19
• Gene ID: 149461
• mRNA Refseq: NM_001123395
• Protein Refseq: NP_001116867
• MIM: 610036
• UniProt ID: Q8N6F1