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Official Full Name cyclic nucleotide gated channel alpha 3
Background Cyclic nucleotide-gated cation channel alpha-3 is a protein that in humans is encoded by the CNGA3 gene.
Synonyms CNGA3; cyclic nucleotide gated channel alpha 3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CNGA3-157H Recombinant Human CNGA3 protein, GST-tagged E. coli GST
    Human CNGA3-11377H Recombinant Human CNGA3, His-tagged E.coli His
    Human CNGA3-1557H Recombinant Human CNGA3 Protein, GST-tagged Wheat Germ GST
    Human CNGA3-7410HCL Recombinant Human CNGA3 293 Cell Lysate HEK293 N/A
    Mouse CNGA3-3646M Recombinant Mouse CNGA3 Protein Mammalian Cell His
    Chicken CNGA3-6774C Recombinant Chicken CNGA3 Mammalian Cell His

    cnga3 involved in several pathways and played different roles in them. We selected most pathways cnga3 participated on our site, such as Olfactory transduction, Visual signal transduction: Cones, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with cnga3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Olfactory transduction OLFR510; SLC8A1; OLFR473; OR8A1; OR1L6; OR10A5; OR6Q1; OLFR486; OLFR493; OLFR50
    Visual signal transduction: Cones CNGA3; ARR3; RLN1; RDH12; GRK7
    cAMP signaling pathway ATP1A2; VAV2; GRIA3; EP300; HTR1A; PPP1R12A; CREB3L3; NFKBIA; FOS; MAPK9

    cnga3 has several biochemical functions, for example, cGMP binding, intracellular cAMP activated cation channel activity, intracellular cGMP activated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cnga3 itself. We selected most functions cnga3 had, and list some proteins which have the same functions with cnga3. You can find most of the proteins on our site.

    Function Related Protein
    intracellular cAMP activated cation channel activity HCN4; CNGA4; CNGA5; CNGA1; HCN2; CNGA3
    intracellular cGMP activated cation channel activity CNGA1; CNGA2; AQP1; CNGA3; CNGA4; CNGA5
    ligand-gated ion channel activity CHRNA4; Chrng; CLCA5; CHRNB2; TRPA1A; CHRNB1; CHRNA3; GABRB1; CLCA2; ANXA6
    voltage-gated potassium channel activity KCNAB2; KCND2; KCNH2A; KCNQ1; KCNA1; KCNJ11; KCNE4; KCNT1; KCNQ3; KCNQ5

    cnga3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cnga3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cnga3.


    Selvakumar, D; Drescher, MJ; et al. CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1. BIOCHEMICAL JOURNAL 443:463-476(2012).
    Chao, YC; Cheng, CJ; et al. Guanylate cyclase-G, expressed in the Grueneberg ganglion olfactory subsystem, is activated by bicarbonate. BIOCHEMICAL JOURNAL 432:267-273(2010).

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