CNOT1
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Official Full Name
CNOT1 CCR4-NOT transcription complex, subunit 1 [ Homo sapiens ] -
Synonyms
CCR4-NOT transcription complex, subunit 1;CCR4-associated factor 1;NOT1;AD-005;CDC39;adrenal gland protein AD-005;NOT1H;CCR4-NOT transcription complex subunit 1;KIAA1007;NOT1 (negative regulator of transcription 1, yeast) homolog;Negative regulator of transcription subunit 1 homolog;hNOT1;CNOT1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CNOT1-11393H | Recombinant Human CNOT1, His-tagged | E.coli | Human | His | 1-354a.a. | |
| CNOT1-1576H | Recombinant Human CNOT1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CNOT1-4731C | Recombinant Chicken CNOT1 | Mammalian Cells | Chicken | His |
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| CNOT1-4911Z | Recombinant Zebrafish CNOT1 | Mammalian Cells | Zebrafish | His |
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Involved Pathway
CNOT1 involved in several pathways and played different roles in them. We selected most pathways CNOT1 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNOT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | CNOT4B,CNOT7,PAPD7,TOB1,BTG3,EDC4,TOB2,CNOT2,ENO2,DDX6 |
Protein Function
CNOT1 has several biochemical functions, for example, armadillo repeat domain binding,estrogen receptor binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNOT1 itself. We selected most functions CNOT1 had, and list some proteins which have the same functions with CNOT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| retinoic acid receptor binding | ASXL1,MED1,AASS,HMGA1-RS1,ACTN4,PRAMEF10,PRAMEF1,SNW1,HMGA1,NSD1 |
| protein complex scaffold | SLC9A1,AXIN1,CAV1,SEPT2,MAGI1,MAGI1B,SMARCD1,AKAP6,SLC9A3R1,CAV3 |
| estrogen receptor binding | LEF1,DYX1C1,PPARGC1A,PCNA,ARRB1,CTNNB1,ISL1,PRMT2,FUS,DDX5 |
| protein binding | TFR2,PENK,MSX2,KIR2DL3,FBXL14,TMEM123,ZBTB8A,NUP62,FAM162A,RRS1 |
| poly(A) RNA binding | NOVA2,DHX16,SR140,LBR,C14orf21,DDX39A,MEX3C,CRNKL1,CDK11B,DDX50 |
| protein domain specific binding | GUSB,WNT1,WHRN,ATP1A1,GNAI3,PPP3R1,Akap2,SNCA,CASP2,IST1 |
| armadillo repeat domain binding | LEF1,AXIN1,STRN4,CALCOCO1,TCF7L2,STRN,CTNNBIP1,AXIN2,CHD8 |
| contributes_to poly(A)-specific ribonuclease activity | PAN3,CNOT2 |
Interacting Protein
CNOT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNOT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNOT1.
CNOT8;CNOT7;CNOT6L;CNOT6
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References
- Turowski, TW; et al. The impact of transcription on posttranscriptional processes in yeast. GENE 526:23-29(2013).
- Moura, R; Pontillo, A; et al. Exome analysis of HIV patients submitted to dendritic cells therapeutic vaccine reveals an association of CNOT1 gene with response to the treatment. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY 17:-(2014).
