Col4a4
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Official Full Name
collagen, type IV, alpha 4
Recombinant Proteins
- Human
- Mouse
- Mammalian Cells
- HEK293
- E.coli
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COL4A4-180H | Recombinant Human COL4A4 | Mammalian Cells | Human | His |
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| COL4A4-3739M | Recombinant Mouse COL4A4 Protein | Mammalian Cells | Mouse | His |
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| COL4A4-1866M | Recombinant Mouse COL4A4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| COL4A4-1866M-B | Recombinant Mouse COL4A4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| COL4A4-2715H | Recombinant Human COL4A4 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| COL4A4-2715H-B | Recombinant Human COL4A4 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| COL4A4-333H | Recombinant Human COL4A4 Protein, His-tagged | E.coli | Human | His | Val1469~Ser1690 |
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Involved Pathway
Col4a4 involved in several pathways and played different roles in them. We selected most pathways Col4a4 participated on our site, such as Amoebiasis,Assembly of collagen fibrils and other multimeric structures,Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Col4a4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amoebiasis | LAMB1,IL1B2,PLCB1,ARG2,CXCL8,SERPINB9,PTK2,Itgam&Itgb2,PRKCA,SERPINB10 |
| Collagen formation | COL28A1,CTSL2,SERPINH1A,CTSL1,LOXL1,LOX,COL19A1,COL16A1,ADAMTS2,MMP13 |
| Extracellular matrix organization | CEACAM8,COMP,DDR1,COL17A1A,COL4A3,LOXL3,LEPREL2,DDR2,TRAPPC4,COL16A1 |
| Collagen biosynthesis and modifying enzymes | PCOLCE2B,COL17A1A,COL28A1D,COL17A1,COL1A2,COL23A1,COL9A1B,COL19A1,BMP1,SERPINH1B |
| Axon guidance | NRP1,CLTC,MYL9,COL6A3,KIF4,PAK6,GPC1B,SPTBN2,LIMK2,ABLIM1 |
| ECM-receptor interaction | COL27A1A,COL6A1,VTNB,COL27A1B,ITGB1,ITGB5,COL1A1B,LAMA3,GP5,THBS4 |
| Developmental Biology | DUSP1,CLASP1,SCN4A,ARPC4,MYOD1,PRDM14,NR5A1,MED7,CLTA,SCN2B |
| Assembly of collagen fibrils and other multimeric structures | BMP1A,CTSL2,PCOLCE,COL3A1,DST,COL5A2,MMP13,CD151,LOXL2,COL6A2 |
Protein Function
Col4a4 has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by Col4a4 itself. We selected most functions Col4a4 had, and list some proteins which have the same functions with Col4a4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent | BGN,FBLN2,COL11A1B,TINAGL1,KAL1,COL27A1,CD4,COL5A1,CHI3L1,LAMA4 |
Interacting Protein
Col4a4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Col4a4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Col4a4.
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References
- Yao, XD; Chen, X; et al. Challenge in pathologic diagnosis of Alport syndrome: evidence from correction of previous misdiagnosis. ORPHANET JOURNAL OF RARE DISEASES 7:-(2012).
- Heidet, L; Borza, DB; et al. A human-mouse chimera of the a3a4a5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice. AMERICAN JOURNAL OF PATHOLOGY 163:1633-1644(2003).
