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Official Full Name collagen, type IV, alpha 4
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL4A4-180H Recombinant Human COL4A4 Mammalian Cell His
    Human COL4A4-333H Recombinant Human COL4A4 Protein, His-tagged E.coli His
    Mouse COL4A4-3739M Recombinant Mouse COL4A4 Protein Mammalian Cell His

    col4a4 involved in several pathways and played different roles in them. We selected most pathways col4a4 participated on our site, such as Amoebiasis, Assembly of collagen fibrils and other multimeric structures, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with col4a4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amoebiasis COL5A1; COL4A5; RAB5C; C8G; LAMB1; LAMA4; IFNG; PLCB3; GNAQ; PRKCB
    Assembly of collagen fibrils and other multimeric structures PCOLCE; BMP1A; CTSL1; COL10A1; COL8A1; BMP1B; ABHD1; LOX; COL6A2; CTSB
    Axon guidance COL9A3; FGFR1B; ABLIM2; ITSN1; EPHA3; CXCR4; DLG3; CDK5; SEMA6B; EPHB6
    Collagen biosynthesis and modifying enzymes PCOLCE2B; LEPRE1; P3H2; COL5A3B; PCOLCE; ADAMTS3; COL23A1; COL17A1; COL15A1B; COL2A1
    Collagen formation COL4A5; BMP1A; COL16A1; COL1A1; LOX; PPIB; COL23A1; COL2A1; COL25A1; LOXL4
    Developmental Biology MED18; SEMA3A; EPHA2; ADAM23; CDK8; PEA15A; TRPC4; ANK2B; PLXNC1; TCF12
    ECM-receptor interaction ITGA1; LAMC3; ITGB3B; GP5; COL6A1; VTNB; ITGA3B; TNN; LAMA5; ITGB4
    Extracellular matrix organization JAM2B; SERPINH1A; ADAM15; DST; MGC174155; TIMP2B; CD151; COL9A1A; LOC100514666; BMP1A

    col4a4 has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by col4a4 itself. We selected most functions col4a4 had, and list some proteins which have the same functions with col4a4. You can find most of the proteins on our site.

    Function Related Protein
    extracellular matrix structural constituent MGP; LAMC1; PXDN; COL27A1; COL5A1; ELN; COL1A1A; COL2A1B; COL11A1B; ACAN

    col4a4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with col4a4 here. Most of them are supplied by our site. Hope this information will be useful for your research of col4a4.


    Yao, XD; Chen, X; et al. Challenge in pathologic diagnosis of Alport syndrome: evidence from correction of previous misdiagnosis. ORPHANET JOURNAL OF RARE DISEASES 7:-(2012).
    Heidet, L; Borza, DB; et al. A human-mouse chimera of the a3a4a5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice. AMERICAN JOURNAL OF PATHOLOGY 163:1633-1644(2003).

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