col6a2

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col6a2

Official Full Name collagen, type VI, alpha 2
Background This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
Synonyms COL6A2; collagen, type VI, alpha 2; collagen alpha-2(VI) chain; Collagen alpha 2(VI) chain; Collagen VI alpha 2 polypeptide; PP3610; OTTHUMP00000115568; OTTHUMP00000115569; OTTHUMP00000115570; collagen VI, alpha-2 polypeptide; human mRNA for collagen VI alpha-2 C-terminal globular domain
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL6A2-2168H Recombinant Human COL6A2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human COL6A2-2710H Recombinant Human COL6A2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Col6a2-918M Recombinant Mouse Col6a2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human COL6A2-11439H Recombinant Human COL6A2, GST-tagged E.coli GST
    Human COL6A2-1660H Recombinant Human COL6A2 Protein, GST-tagged Wheat Germ GST
    Human COL6A2-28H Recombinant Human COL6A2 protein, T7/His-tagged E.coli T7/His
    Human COL6A2-3282H Recombinant Human COL6A2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human COL6A2-382HCL Recombinant Human COL6A2 cell lysate N/A
    Mouse COL6A2-3746M Recombinant Mouse COL6A2 Protein Mammalian Cell His
    Chicken COL6A2-6900C Recombinant Chicken COL6A2 Mammalian Cell His

    col6a2 involved in several pathways and played different roles in them. We selected most pathways col6a2 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Axon guidance, Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with col6a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of collagen fibrils and other multimeric structures COL1A1; COL10A1A; COL10A1; TLL2; COL4A4; CTSB; TLL1; CTSS; COL1A2; ABHD1
    Axon guidance SPNA2; PPP3CB; CSF2; CXCL12; SPTBN1; GDNF; NEFLB; PAQR3B; RNF8; EPHB6
    Collagen biosynthesis and modifying enzymes COL6A1; COL4A5; BMP1A; SERPINH1A; COL5A3A; LEPREL1; COL25A1; COL10A1A; COL6A3; LEPRE1
    Collagen formation COL8A1; LOXL4; COL4A3; COL8A2; CTSL2; COL6A3; MMP13; TLL1; LEPREL2; COL10A1
    Developmental Biology CLTC; RND1L; TCF12; SCN3A; SEMA3AB; PRDM14; SMAD3B; CD24; ITGB3A; DPYSL5A
    ECM-receptor interaction VTNA; COL5A1; COL6A5; ITGA6; Reln; COL4A6; SV2B; COL1A1; ITGA3; ITGA3B
    Extracellular matrix organization MGC174857; ICAM4; COL6A2; MMP12; ADAM8A; PCOLCEA; F11R.2; COL5A1; PCOLCE; LAMB1B
    Focal Adhesion MYL9; PIP5K1C; PAK6B; STYK1; BCL2; MYLK; COL5A1; PPP1CA; RAP1AB; RAF1B

    col6a2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by col6a2 itself. We selected most functions col6a2 had, and list some proteins which have the same functions with col6a2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding DEAF1; CD200R3; HIRA; MCEE; OBFC1; MATN1; KCTD6; KRT14; VPS72; PKN3

    col6a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with col6a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of col6a2.

    COX6A2; TFAP2C; SLC38A3; DISC1

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