|Official Full Name||collagen, type VI, alpha 2|
|Background||This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.|
|Synonyms||COL6A2; collagen, type VI, alpha 2; collagen alpha-2(VI) chain; Collagen alpha 2(VI) chain; Collagen VI alpha 2 polypeptide; PP3610; OTTHUMP00000115568; OTTHUMP00000115569; OTTHUMP00000115570; collagen VI, alpha-2 polypeptide; human mRNA for collagen VI alpha-2 C-terminal globular domain|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
col6a2 involved in several pathways and played different roles in them. We selected most pathways col6a2 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Axon guidance, Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with col6a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Assembly of collagen fibrils and other multimeric structures||COL1A1; COL10A1A; COL10A1; TLL2; COL4A4; CTSB; TLL1; CTSS; COL1A2; ABHD1|
|Axon guidance||SPNA2; PPP3CB; CSF2; CXCL12; SPTBN1; GDNF; NEFLB; PAQR3B; RNF8; EPHB6|
|Collagen biosynthesis and modifying enzymes||COL6A1; COL4A5; BMP1A; SERPINH1A; COL5A3A; LEPREL1; COL25A1; COL10A1A; COL6A3; LEPRE1|
|Collagen formation||COL8A1; LOXL4; COL4A3; COL8A2; CTSL2; COL6A3; MMP13; TLL1; LEPREL2; COL10A1|
|Developmental Biology||CLTC; RND1L; TCF12; SCN3A; SEMA3AB; PRDM14; SMAD3B; CD24; ITGB3A; DPYSL5A|
|ECM-receptor interaction||VTNA; COL5A1; COL6A5; ITGA6; Reln; COL4A6; SV2B; COL1A1; ITGA3; ITGA3B|
|Extracellular matrix organization||MGC174857; ICAM4; COL6A2; MMP12; ADAM8A; PCOLCEA; F11R.2; COL5A1; PCOLCE; LAMB1B|
|Focal Adhesion||MYL9; PIP5K1C; PAK6B; STYK1; BCL2; MYLK; COL5A1; PPP1CA; RAP1AB; RAF1B|
col6a2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by col6a2 itself. We selected most functions col6a2 had, and list some proteins which have the same functions with col6a2. You can find most of the proteins on our site.
|protein binding||DEAF1; CD200R3; HIRA; MCEE; OBFC1; MATN1; KCTD6; KRT14; VPS72; PKN3|
col6a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with col6a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of col6a2.
COX6A2; TFAP2C; SLC38A3; DISC1