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Official Full Name collagen, type IX, alpha 1
Background This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Synonyms COL9A1; collagen, type IX, alpha 1; MED; EDM6; STL4; DJ149L1.1.2
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL9A1-11442H Recombinant Human COL9A1, GST-tagged E.coli GST
    Human COL9A1-147H Recombinant Human COL9A1, His tagged Human Cell Fc
    Human COL9A1-1663H Recombinant Human COL9A1 Protein, GST-tagged Wheat Germ GST
    Human COL9A1-265H Recombinant Human COL9A1, Fc-tagged Human Cell Fc
    Human COL9A1-3298H Recombinant Human COL9A1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human COL9A1-4078H Recombinant Human COL9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human COL9A1-5853H Recombinant Human COL9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human COL9A1-758HCL Recombinant Human COL9A1 cell lysate Human Cell N/A
    Human COL9A1-796HCL Recombinant Human COL9A1 cell lysate Human Cell N/A
    Mouse Col9a1-919M Recombinant Mouse Col9a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Col9a1-336R Recombinant Rat Col9a1 Protein, His-tagged E.coli N/A
    Chicken COL9A1-3731C Recombinant Chicken COL9A1 Mammalian Cell His

    col9a1 involved in several pathways and played different roles in them. We selected most pathways col9a1 participated on our site, such as Axon guidance, Collagen biosynthesis and modifying enzymes, Collagen degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with col9a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance NFATC4; NRP2; TRIO; EFNB2A; EFNB3; RND1L; HRAS; SEMA3C; RNF8; PAQR3B
    Collagen biosynthesis and modifying enzymes COL6A1; COL11A1B; COL8A1; BMP1; COL5A2; LEPRE1; PPIB; COL9A3; PCOLCE; TLL1
    Collagen degradation MMP11; CTSK; TLDC2; CTSB; CTSD; MMP15; LOC100686744; COL19A1; MGC174152; COL25A1
    Collagen formation COL23A1; COL3A1; COL4A5; COL9A1B; COL2A1; COL9A3; COL17A1A; CTSL2; MMP20; TLL1
    Degradation of the extracellular matrix MMP15; TPSAB1; ADAMTS5; MMP17; COL9A3; ACAN; MMP12; BMP1B; COL25A1; MMP10
    Developmental Biology CCNC; RANBP9; FGFR1B; SEMA4D; KBTBD7; DUSP1; EFNA5; EFNA1A; CLTA; DPYSL2
    Extracellular matrix organization TTR; CEACAM1; LEPREL2; TLL1; LOXL4; LEPREL1; ADAMTS18; TIMP2B; HAPLN1; BMP10

    col9a1 has several biochemical functions, for example, extracellular matrix structural constituent conferring tensile strength, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by col9a1 itself. We selected most functions col9a1 had, and list some proteins which have the same functions with col9a1. You can find most of the proteins on our site.

    Function Related Protein
    extracellular matrix structural constituent conferring tensile strength COL9A3; COL9A1; COL2A1
    metal ion binding GLRX2; ZFP184; RC3H1; WBP7; MARCH9; Car9; ZFP428; SUZ12B; ZNF428; PAPL

    col9a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with col9a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of col9a1.

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