COX18 Protein

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COX18

Official Full Name	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
Background	COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of;the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the;assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 (PubMed 16212937)).
Synonyms	COX18; COX18 cytochrome c oxidase assembly homolog (S. cerevisiae); mitochondrial inner membrane protein COX18; FLJ38991; COII; COX2; COX2_HUMAN; COXII; Cytochrome c oxidase II; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; MS405; MS419; MT CO2; MT-CO2; MTCO2; Cox18Hs1 protein; Cox18Hs2 protein; Cox18Hs3 protein; OTTHUMP00000160366; OTTHUMP00000219030; mitochondrial COX18; cytochrome c oxidase assembly protein 18; COX18HS;

Type:
Recombinant Proteins

Species :
Human
Mouse
Mus musculus (Mouse)

Source :
E.coli
E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)-Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	COX18-11489H	Recombinant Human COX18, GST-tagged	E.coli	GST	Inquiry
Human	COX18-1740H	Recombinant Human COX18 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Mouse	COX18-3811M	Recombinant Mouse COX18 Protein	Mammalian Cell	His	Inquiry
Mouse	COX18-1912M	Recombinant Mouse COX18 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	COX18-2001HF	Recombinant Full Length Human COX18 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry
Mus musculus (Mouse)	RFL1417MF	Recombinant Full Length Mouse Mitochondrial Inner Membrane Protein Cox18(Cox18) Protein, His-Tagged	E.coli expression system	His	Inquiry

Involved Pathway Protein Function Interacting Protein COX18 Related Articles

COX18 involved in several pathways and played different roles in them. We selected most pathways COX18 participated on our site, such as Gene Expression, Generic Transcription Pathway, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	ZNF776; TRIM33; IPO8; EARS2; SAP30BP; DNAJC8; MTF2; NR6A1A; RBB4L; MTERF
Generic Transcription Pathway	TEAD3B; ZNF114; ZNF486; ZNF133; CDK9; ZNF317; ZNF471; ZIK1; JUNB; RRAGA
Metabolism	DAO1; ARSE; APOA5; COX6B1; ADSS; ADH8B; COX16; NUDT15; INSIG1; PPP1R2
Respiratory electron transport	COX18; NDUFAF2; NDUFAF3; SURF1; NDUFAF6; COX16; SCO1; ETFB; NDUFAF4; NDUFAF7
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	NDUFAF4; COX16; TIMMDC1; NDUFAF7; NDUFAF5; C20orf7; SCO1; ETFDH; COX11; NDUFAF2
TP53 Regulates Metabolic Genes	TACO1; COX14; LRPPRC; SURF1; COX18; SCO1; PRDX2; FAM36A; SESN3; COX16
The citric acid (TCA) cycle and respiratory electron transport	PDP1; C2orf56; ATP5L; NDUFAF5; FAM36A; PDK4; NDUFAF2; PDP2; NDUFAF6; ETFB
Transcriptional Regulation by TP53	COX16; FAM36A; PRDX2; TACO1; SESN3; COX18; COX14

COX18 has several biochemical functions, for example, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COX18 itself. We selected most functions COX18 had, and list some proteins which have the same functions with COX18. You can find most of the proteins on our site.

Function	Related Protein
protein transporter activity	EIF4ENIF1; COG2; XPO6; IPO4; RAMP3; IPO8; CHMP7; TMCO6; AP1S3B; RAB4A

COX18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX18 here. Most of them are supplied by our site. Hope this information will be useful for your research of COX18.

Vandell, AG; McDonough, CW; et al. Hydrochlorothiazide-induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study. JOURNAL OF INTERNAL MEDICINE 276:486-497(2014).

Goncalves, VF; Zai, CC; et al. A Hypothesis-Driven Association Study of 28 Nuclear-Encoded Mitochondrial Genes with Antipsychotic-Induced Weight Gain in Schizophrenia. NEUROPSYCHOPHARMACOLOGY 39:1347-1354(2014).

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