Recombinant Human COX18, GST-tagged

• Cat.No.: COX18-11489H
• Product Overview: Recombinant Human COX18 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 187-333a.a.
• Description: COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COX18 COX18 cytochrome c oxidase assembly homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: COX18
• Synonyms: COX18; COX18 cytochrome c oxidase assembly homolog (S. cerevisiae); mitochondrial inner membrane protein COX18; FLJ38991; Cox18Hs1 protein; Cox18Hs2 protein; Cox18Hs3 protein; mitochondrial COX18; cytochrome c oxidase assembly protein 18; COX18HS; MGC126733
• Gene ID: 285521
• mRNA Refseq: NM_173827
• Protein Refseq: NP_776188
• MIM: 610428
• UniProt ID: Q8N8Q8
• Chromosome Location: 4q13.3
• Function: protein transporter activity