COX5B

  • Official Full Name

    cytochrome c oxidase subunit Vb

  • Overview

    Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.
  • Synonyms

    COX5B; cytochrome c oxidase subunit Vb; cytochrome c oxidase subunit 5B, mitochondrial; mitochondrial; COX 5B; COX5B_HUMAN; COXVB; Cytochrome c oxidase polypeptide Vb; Cytochrome c oxidase polypeptide VB mitochondrial; Cytochrome c oxidase subunit 5B; Cytochrome c oxidase subunit 5B mitochondrial; OTTHUMP00000161109; cytochrome c oxidase polypeptide VB, mitochondrial;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COX5B-441H Recombinant Human COX5B protein, His-tagged E.coli His Ala32-His129
Human COX5B-11493H Recombinant Human COX5B, GST-tagged E.coli GST 1-129a.a.
Human COX5B-202H Recombinant Human cytochrome c oxidase subunit Vb, His-tagged E.coli His
Human COX5B-1751H Recombinant Human COX5B Protein, GST-tagged Wheat Germ GST
Human COX5B-7332HCL Recombinant Human COX5B 293 Cell Lysate HEK293 N/A
Human COX5B-4604H Recombinant Human COX5B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human COX5B-1783H Recombinant Human COX5B Protein (Ala32-His129), N-GST tagged E.coli N-GST Ala32-His129
Human COX5B-2009HF Recombinant Full Length Human COX5B Protein, GST-tagged In Vitro Cell Free System GST 129 amino acids
Mouse Cox5b-926M Recombinant Mouse Cox5b Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat COX5B-1554R Recombinant Rat COX5B Protein Mammalian Cell His
Rat COX5B-1211R Recombinant Rat COX5B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat COX5B-1211R-B Recombinant Rat COX5B Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

COX5B involved in several pathways and played different roles in them. We selected most pathways COX5B participated on our site, such as Alzheimers disease, Cardiac muscle contraction, Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Alzheimers diseaseNDUFC2-KCTD14;NDUFB2;CALM3;ATP5G3;LRP1;NDUFS1;SDHB;ATP5E;ADAM17
Cardiac muscle contractionVMHC;COX7A1;UQCRC2B;ATP1B2A;CACNG1;COX8C;CACNG3;MYH15;UQCRFS1
Electron Transport ChainNDUFC2-KCTD14;SURF1;SCO1;COX15;COX5B;COX7C;COX11;COX7A2;ATP5S
Gene ExpressionFKBP6;ZNF785;ZNF37A;COX16;MED13B;ZNF3;ZFP30;ZNF133;NRBF2B
Generic Transcription PathwayNR5A1B;ZNF668;ZNF583;ZNF573;ZNF771;ZNF202;HIPK1;ZNF92;ZNF100
Huntingtons diseaseNDUFC1;NDUFA10;SLC25A5;COX5B;NDUFB4;DNAI2;NDUFS5;COX7A2L;COX7B2
Metabolic pathwaysCYP2C8;ETNPPL;GALNT9;GOT1;B3GNT2;RPIA;GALNT13;NME2B.1;SYNJ1
MetabolismPAOX;SLC2A3;CYP3C4;SACM1LB;NOSTRIN;PPARGC1B;STARD5;NHLRC1;PDPR

COX5B has several biochemical functions, for example, cytochrome-c oxidase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COX5B itself. We selected most functions COX5B had, and list some proteins which have the same functions with COX5B. You can find most of the proteins on our site.

Function Related Protein
cytochrome-c oxidase activityCOX11;COX7A2;COX7A1;COA6;SURF1;COX5A;COX6C;COX6B1;COX5B
metal ion bindingDNAJA2;KCND1;KLF12A;CYP2AA4;ZNF726;PDE4A;AMHR2;CYP2D10;PDE2A
protein bindingLRGUK;SNX10;HSD17B12;EML2;AP3M1;DBF4B;MFF;B3GAT3;CALD1

COX5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX5B here. Most of them are supplied by our site. Hope this information will be useful for your research of COX5B.

TRIM23; CCDC36; BHLHE40; KRT15; CDR2; TRAF1

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