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Cox7a2

Official Full Name

COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) [ Homo sapiens ]
Overview

Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
Synonyms

COX7A2; COX7AL; COX7AL1; COXVIIa L; COXVIIAL; CX7A2_HUMAN; Cytochrome c oxidase polypeptide 7A2 mitochondrial; Cytochrome c oxidase polypeptide VIIa liver/heart; Cytochrome c oxidase subunit 7A2; Cytochrome c oxidase subunit 7A2 mitochondrial; Cytochrome c oxidase subunit VIIa polypeptide 2; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; Cytochrome c oxidase subunit VIIaL; Hepatic cytochrome c oxidase chain VIIa; MGC118950; MGC118951; MGC118952; MGC126875; MGC126877; mitochondrial; VIIAL;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	COX7A2-11500H	Recombinant Human COX7A2, GST-tagged	E.coli	GST	1-83a.a.	$319 / 25μg
Human	COX7A2-12H	Recombinant Human COX7A2 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	COX7A2-7326HCL	Recombinant Human COX7A2 293 Cell Lysate	HEK293	Non		Inquiry
Mouse	COX7A2-3823M	Recombinant Mouse COX7A2 Protein	Mammalian Cell	His		Inquiry
Mouse	COX7A2-1920M	Recombinant Mouse COX7A2 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	COX7A2-1920M-B	Recombinant Mouse COX7A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	COX7A2-4224C	Recombinant Chicken COX7A2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Cox7a2 involved in several pathways and played different roles in them. We selected most pathways Cox7a2 participated on our site, such as Alzheimers disease, Cardiac muscle contraction, Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cox7a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Alzheimers disease	GAPDH;NDUFA13;CAPN1;APH1B;BID;PPP3R1;NDUFA7;NDUFAB1;Atp5g2
Cardiac muscle contraction	COX8C;UQCRC1;COX5AA;COX4I1;MYH7;VMHC;TPM4;CACNA2D2;ATP1B3
Electron Transport Chain	UCP3;COX6A2;COX6C;COX6B1;COX4I1;UCP2;ATP5H;COX7C;COX8A
Huntingtons disease	DCTN4;BBC3;NDUFAB1;COX6B1;NDUFA11;DNAL1;TAF4B;POLR2L;DNAI1
Non-alcoholic fatty liver disease (NAFLD)	MAPK9;IL-8;RAC1;PIK3CD;NR1H3;NDUFA6;CASP7;INSR;NDUFC2
Oxidative phosphorylation	COX7A2A;SDHD;ATP5G1;COX5AA;LHPP;ATPV0E2;ATP6V1C2;ATP6V0E2;NDUFC1
Parkinsons disease	SLC6A3;UBE2J1;UCHL1;CYCS;ATP5E;COX7A2;SDHA;UQCRFS1;NDUFS8

Cox7a2 has several biochemical functions, for example, cytochrome-c oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cox7a2 itself. We selected most functions Cox7a2 had, and list some proteins which have the same functions with Cox7a2. You can find most of the proteins on our site.

Function	Related Protein
cytochrome-c oxidase activity	COX7A2A;COX8A;COX5B;COX7A3;COX5B2;COX7C;COX7A2;SURF1;COX7A1

Cox7a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cox7a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cox7a2.