Recombinant Human COX7A2, GST-tagged

• Cat.No.: COX7A2-11500H
• Product Overview: Recombinant Human COX7A2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-83a.a.
• Description: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) [ Homo sapiens ]
• Official Symbol: COX7A2
• Synonyms: COX7A2; COX7AL; COX7AL1; COXVIIa L; COXVIIAL; CX7A2_HUMAN; Cytochrome c oxidase polypeptide 7A2 mitochondrial; Cytochrome c oxidase polypeptide VIIa liver/heart; Cytochrome c oxidase subunit 7A2; Cytochrome c oxidase subunit 7A2 mitochondrial; Cytochrome c oxidase subunit VIIa polypeptide 2; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; Cytochrome c oxidase subunit VIIaL; Hepatic cytochrome c oxidase chain VIIa; MGC118950; MGC118951; MGC118952; MGC126875; MGC126877; mitochondrial; VIIAL
• Gene ID: 1347
• mRNA Refseq: NM_001865.3
• Protein Refseq: NP_001856.2
• MIM: 123996
• UniProt ID: H0UI06
• Chromosome Location: 6q12
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome c oxidase, organism-specific biosystem; Cytochrome c oxidase, conserved biosystem; Electron Transport Chain, organism-specific biosystem
• Function: cytochrome-c oxidase activity; electron carrier activity