• Official Full Name

    cytochrome c oxidase subunit VIIb

  • Background

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.
  • Synonyms

    COX7B; cytochrome c oxidase subunit VIIb; cytochrome c oxidase subunit 7B, mitochondrial; mitochondrial; COX7B_HUMAN; Cytochrome c oxidase chain VIIb; Cytochrome c oxidase polypeptide VIIb; Cytochrome c oxidase subunit 7B; Cytochrome c oxidase subunit 7B mitochondrial; cytochrome-c oxidase chain VIIb;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COX7B-1763H Recombinant Human COX7B Protein, GST-tagged Wheat Germ GST
    Human COX7B-119H Recombinant Human COX7B Protein, His-tagged E.coli His
    Mouse COX7B-3825M Recombinant Mouse COX7B Protein Mammalian Cell His
    Mouse COX7B-1921M Recombinant Mouse COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse COX7B-1921M-B Recombinant Mouse COX7B Protein Pre-coupled Magnetic Beads HEK293
    Rat COX7B-1214R-B Recombinant Rat COX7B Protein Pre-coupled Magnetic Beads HEK293
    Rat COX7B-1214R Recombinant Rat COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat COX7B-1557R Recombinant Rat COX7B Protein Mammalian Cell His
    Rhesus Macaque COX7B-822R Recombinant Rhesus Macaque COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque COX7B-822R-B Recombinant Rhesus Macaque COX7B Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque COX7B-997R Recombinant Rhesus monkey COX7B Protein, His-tagged Mammalian Cell His
    Zebrafish COX7B-7085Z Recombinant Zebrafish COX7B Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • COX7B Related Articles

    COX7B involved in several pathways and played different roles in them. We selected most pathways COX7B participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylationCOX17;ATP5F1;SDHDA;ATP6V1H;NDUFA9A;ATP5S;COX7B2;NDUFC1;SDHB
    Metabolic pathwaysTHA1;HPGDS;ALAS1;RFK;GBA3;UMPS;CYP4F14;ASL;HEXA
    Cardiac muscle contractionTPM3;CACNG2A;ATP1B1;ACTC1;COX5B;ATP1B1A;CACNB1;COX4I1;ATP1B3A
    Non-alcoholic fatty liver disease (NAFLD)NDUFS2;COX7A1;NDUFS8;ADIPOQ;NDUFS3;KCNA3;ATF4;NDUFC2-KCTD14;RXRA
    Huntingtons diseaseATP5C1;NDUFB1;NDUFB4;SLC25A4;UCP1;COX8A;NDUFA2;POLR2D;NDUFA8

    COX7B has several biochemical functions, for example, cytochrome-c oxidase activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by COX7B itself. We selected most functions COX7B had, and list some proteins which have the same functions with COX7B. You can find most of the proteins on our site.

    Function Related Protein
    cytochrome-c oxidase activityCOX7A2A;COX6C;COX8A;COX7A2L;SURF1;COX6B1;COX7A3;COX8C;CYB5A

    COX7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX7B here. Most of them are supplied by our site. Hope this information will be useful for your research of COX7B.

    Nijtmans, LGJ; Taanman, JW; et al. Assembly of cytochrome-c oxidase in cultured human cells. EUROPEAN JOURNAL OF BIOCHEMISTRY 254:389-394(1998).
    Arnold, S; Lee, I; et al. The subunit structure of cytochrome-c oxidase from tuna heart and liver. EUROPEAN JOURNAL OF BIOCHEMISTRY 248:99-103(1997).
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