COX7B Protein


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Official Full Name cytochrome c oxidase subunit VIIb
Background Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.
Synonyms COX7B; cytochrome c oxidase subunit VIIb; cytochrome c oxidase subunit 7B, mitochondrial; mitochondrial; COX7B_HUMAN; Cytochrome c oxidase chain VIIb; Cytochrome c oxidase polypeptide VIIb; Cytochrome c oxidase subunit 7B; Cytochrome c oxidase subunit 7B mitochondrial; cytochrome-c oxidase chain VIIb
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COX7B-119H Recombinant Human COX7B Protein, His-tagged E.coli His
    Human COX7B-1763H Recombinant Human COX7B Protein, GST-tagged Wheat Germ GST
    Mouse COX7B-3825M Recombinant Mouse COX7B Protein Mammalian Cell His
    Rat COX7B-1557R Recombinant Rat COX7B Protein Mammalian Cell His
    Rhesus Macaque COX7B-997R Recombinant Rhesus monkey COX7B Protein, His-tagged Mammalian Cell His
    Zebrafish COX7B-7085Z Recombinant Zebrafish COX7B Mammalian Cell His
    Human COX7B-2016HF Recombinant Full Length Human COX7B Protein, GST-tagged In Vitro Cell Free System GST

    COX7B involved in several pathways and played different roles in them. We selected most pathways COX7B participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation COX6B2; Atp5k; ATPV0E2; ATP5D; COX7A2L; ATP5IA; NDUFB8; ATP5C1; MT-ATP6; NDUFA9A
    Metabolic pathways B3GNT4; B4GALT2; UGT1A6B; PIGYL; HMBSA; ALDH1B1; PI4K2B; NAPRT; LSS; PNLIPRP2
    Cardiac muscle contraction ATP1B2B; ATP1A3; CACNG6; CACNG7A; TNNC1; CACNB2; UQCRB; TPM3; ATP1B1; CACNA1SB
    Non-alcoholic fatty liver disease (NAFLD) COX7A2; PIK3CA; TNF; COX8C; Casp3; COX6B2; RELA; SREBF1; TGFB1; UQCRB
    Alzheimers disease COX8C; COX8A; CAPN1; NDUFA4L2; EIF2AK3; Atp5g2; PLCB1; COX7A2; UQCRFS1; UQCRH
    Parkinsons disease UBE2G1; COX6B2; UBA1; NDUFA8; NDUFA11; NDUFB9; ATP5G1; UBE2L3; UQCRH; VDAC1
    Huntingtons disease COX8A; SLC25A5; CASP9; NDUFA11; NDUFA4L2; HAP1; HTT; NDUFA8; COX6B1; GRIN1

    COX7B has several biochemical functions, for example, cytochrome-c oxidase activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by COX7B itself. We selected most functions COX7B had, and list some proteins which have the same functions with COX7B. You can find most of the proteins on our site.

    Function Related Protein
    cytochrome-c oxidase activity COX6C; COX7A1; COX5B2; COX6B1; COX7B; COX7A3; COX7A2A; COX15; CYB5A; COX7B2
    molecular_function YDJC; CEACAM10; MBLAC1; VWA5B2; HIST3H2BB; KIZ; WBP1LB; OTOL1; EFCAB5; SMG8

    COX7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX7B here. Most of them are supplied by our site. Hope this information will be useful for your research of COX7B.

    Nijtmans, LGJ; Taanman, JW; et al. Assembly of cytochrome-c oxidase in cultured human cells. EUROPEAN JOURNAL OF BIOCHEMISTRY 254:389-394(1998).
    Arnold, S; Lee, I; et al. The subunit structure of cytochrome-c oxidase from tuna heart and liver. EUROPEAN JOURNAL OF BIOCHEMISTRY 248:99-103(1997).

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