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COX7B

  • Official Full Name

    cytochrome c oxidase subunit VIIb

  • Overview

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.
  • Synonyms

    COX7B; cytochrome c oxidase subunit VIIb; cytochrome c oxidase subunit 7B, mitochondrial; mitochondrial; COX7B_HUMAN; Cytochrome c oxidase chain VIIb; Cytochrome c oxidase polypeptide VIIb; Cytochrome c oxidase subunit 7B; Cytochrome c oxidase subunit 7B mitochondrial; cytochrome-c oxidase chain VIIb;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COX7B-1763H Recombinant Human COX7B Protein, GST-tagged Wheat Germ GST
Human COX7B-119H Recombinant Human COX7B Protein, His-tagged E.coli His
Human COX7B-2016HF Recombinant Full Length Human COX7B Protein, GST-tagged In Vitro Cell Free System GST 80 amino acids
Mouse COX7B-3825M Recombinant Mouse COX7B Protein Mammalian Cell His
Mouse COX7B-1921M Recombinant Mouse COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse COX7B-1921M-B Recombinant Mouse COX7B Protein Pre-coupled Magnetic Beads HEK293
Rat COX7B-1557R Recombinant Rat COX7B Protein Mammalian Cell His
Rat COX7B-1214R Recombinant Rat COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat COX7B-1214R-B Recombinant Rat COX7B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque COX7B-997R Recombinant Rhesus monkey COX7B Protein, His-tagged Mammalian Cell His
Rhesus Macaque COX7B-822R-B Recombinant Rhesus Macaque COX7B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque COX7B-822R Recombinant Rhesus Macaque COX7B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish COX7B-7085Z Recombinant Zebrafish COX7B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • COX7B Related Articles

COX7B involved in several pathways and played different roles in them. We selected most pathways COX7B participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationNDUFV2;NDUFA9A;SDHA;ATP5G1;ATP6AP2;NDUFA3;ATP6V0D1;SDHDA;PPA1B
Metabolic pathwaysITPKA;UGT1A2;GALNTL5;BTD;GALNTL6;CRYL1;AOX1;UCK2B;GOT2A
Cardiac muscle contractionATP1A1A.1;CACNG7;ATP1B2;TNNI3;UQCR10;COX8A;COX5B2;TPMA;TNNT2A
Non-alcoholic fatty liver disease (NAFLD)UQCRC2;TGFB1;ATF4;IL6R;NDUFA1;COX6B2;LEP;NDUFA4;CYCS
Alzheimers diseaseGRIN2D;PLCB4;NDUFB8;NDUFA10;APAF1;NDUFB10;NDUFB1;NAE1;COX6A1
Parkinsons diseaseUBA1;SLC18A1;COX7A1;SLC18A2;UBE2J1;HTRA2;VDAC1;COX8C;NDUFV2
Huntingtons diseaseCYCS;NDUFA10;NDUFS3;NDUFB6;CREB3L2;DNAL1;NDUFS7;HDAC1;DNAH14

COX7B has several biochemical functions, for example, cytochrome-c oxidase activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by COX7B itself. We selected most functions COX7B had, and list some proteins which have the same functions with COX7B. You can find most of the proteins on our site.

Function Related Protein
cytochrome-c oxidase activityCOX6B2;COX5B2;SURF1;COX7A1;COX6C;COX7B2;COX6B1;COX5AA;COA6
molecular_functionCCDC171;GM4952;SETD1B;OSCP1A;SLC46A3;CTU1;MUM1L1;ADAMTS10;LRRC34

COX7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX7B here. Most of them are supplied by our site. Hope this information will be useful for your research of COX7B.

Nijtmans, LGJ; Taanman, JW; et al. Assembly of cytochrome-c oxidase in cultured human cells. EUROPEAN JOURNAL OF BIOCHEMISTRY 254:389-394(1998).
Arnold, S; Lee, I; et al. The subunit structure of cytochrome-c oxidase from tuna heart and liver. EUROPEAN JOURNAL OF BIOCHEMISTRY 248:99-103(1997).
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