CP
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Official Full Name
Ceruloplasmin
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Overview
The protein encoded by this gene is a copper-containing glycoprotein found soluble in the serum and GPI-anchored in other tissues. It oxidizes Fe(II) to Fe(III) and is proposed to play an important role in iron homeostasis. In humans mutations of this gene cause aceruloplasminemia, which is characterized by retinal degeneration, diabetes, anemia and neurological symptoms. In mouse deficiency of this gene in combination with a deficiency of its homolog hephaestin causes retinal degeneration and serves as a pathophysiological model for aceruloplasminemia and age-related macular degeneration. Alternative splicing results in multiple transcript variants that encode different protein isoforms. -
Synonyms
Cp; ceruloplasmin; D3Ertd555e; ferroxidase; CERU_HUMAN; Ceruloplasmin precursor; CP 2; CP2; caeruloplasmin; ceruloplasmin (ferroxidase); OTTHUMP00000197026; OTTHUMP00000215840; OTTHUMP00000215841; CERU_HUMAN; Ceruloplasmin precursor; EC 1.16.3.1; CP2Ferroxidase;
- Recombinant Proteins
- Native Proteins
- Transfected Stable Cell Lines
- Assay Kits
- Bacteriophage MS2
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- Human plasma
- Human Plasma
- Mammalian Cell
- Mouse Serum
- Rat Serum
- C
- His
- GST
- Myc
- His|T7
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CP-01C | Recombinant Chlamydia pneumonia antigen, His-tagged | E.coli | His | 160 amino acids |
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| Human | CP-11507H | Recombinant Human CP, GST-tagged | E.coli | GST | 194-446a.a. | |
| Human | CP-5625H | Recombinant Human CP protein, His-tagged | E.coli | His | Asp789~Gly1065 (Accession # P00450) |
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| Human | CP-2718H | Recombinant Human CP protein, His&Myc-tagged | E.coli | His&Myc | 807-1050aa |
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| Human | CP-8073H | Native Human Plasma Ceruloplasmin | Human Plasma | N/A |
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| Human | CP-26450TH | Native Human CP | N/A |
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| Human | CP-5326H | Native Human Ceruloplasmin (ferroxidase) | Human Plasma | N/A |
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| Human | CP-2496H | Recombinant Human CP protein(731-1060 aa), C-His-tagged | E. coli | C-His | 731-1060 aa |
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| Human | CP-1767H | Native Human CP Protein | Human plasma | N/A |
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| Mouse | Cp-5626M | Recombinant Mouse Cp protein, His & T7-tagged | E.coli | His/T7 | Tyr729~Gly1061 (Accession # Q61147) |
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| Mouse | Cp-832M | Recombinant Mouse Cp Protein, His&GST-tagged | E.coli | N-His&GST | Glu57-Arg87 |
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| Mouse | Cp-674M | Native Mouse Ceruloplasmin | Mouse Serum | N/A |
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| Mouse | CP-8074M | Native Mouse Serum Ceruloplasmin | Mouse Serum | N/A |
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| Rat | Cp-5627R | Recombinant Rat Cp protein, His & T7-tagged | E.coli | His/T7 | Ala872~Gly1059 (Accession # P13635) |
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| Rat | Cp-048R | Native Rat Ceruloplasmin | Rat Serum | N/A |
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| Rat | CP-8075R | Native Rat Serum Ceruloplasmin | Rat Serum | N/A |
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| Rat | Cp-74R | Rat Ceruloplasmin Reference Standard | N/A |
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| Bacteriophage MS2 | CP-4270B | Recombinant Bacteriophage MS2 CP protein, His&Myc-tagged | E.coli | His&Myc | 2-130aa |
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| Zebrafish | CP-9314Z | Recombinant Zebrafish CP | Mammalian Cell | His |
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| Kit-0257 | CP Colorimetric Assay Kit | N/A |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CP Related Articles
CP involved in several pathways and played different roles in them. We selected most pathways CP participated on our site, such as HIF-1-alpha transcription factor network, Iron uptake and transport, Metal ion SLC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with CP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HIF-1-alpha transcription factor network | COPS5;ENG;EGLN3;TFF3;PLIN2;CITED2;GATA2;ADM;NPM1 |
| Iron uptake and transport | FTH1A;LCN2;ABCG2D;ATP6V1G3;TFR1B;TFA;FLVCR1;CP;MFSD7B |
| Metal ion SLC transporters | SLC39A3;SLC39A5;SLC30A1A;CP;SLC30A8;SLC39A14;SLC39A7;SLC30A3;SLC39A6 |
| Porphyrin and chlorophyll metabolism | BLVRA;MMAB;ALAS1;UGT1A6;EPRS;UGT2B15;CPOX;HMBSA;UGT2A3 |
| SLC-mediated transmembrane transport | SLC7A3A;SLC44A5B;SLC34A2A;SLC26A2;SLC6A6;SLC35A3B;RHCG;SLC39A1;SLC1A3B |
| Transmembrane transport of small molecules | ANO1;BSND;ADD3;SLC34A3;AQP10;CLCN4;SLC26A3;SLC12A7;CUTC |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | RHCGB;SLC39A10;SLC39A6;SLC13A4;SLC31A1;SLC22A7;SLC30A3;SLC13A1;SLC22A7A |
CP has several biochemical functions, for example, chaperone binding, copper ion binding, ferroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CP itself. We selected most functions CP had, and list some proteins which have the same functions with CP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chaperone binding | TBCE;RNF207;DNAJA2;Alb;BAG4;HSPD1;DNAJC3;INS1;BAG1 |
| copper ion binding | CUTC;TRP53;PRNPA;AOC3;SNCA;SOD1;CCC2;S100V2;PRND |
| ferroxidase activity | CP;FTH1;FXN;FTMT;HEPH;HEPHL1 |
CP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CP here. Most of them are supplied by our site. Hope this information will be useful for your research of CP.
iron2plus; SLC40A1; q8cl89_yerpe; BTRC; d-mannose; IGHG1; APOA1
- Q&As
- Reviews
Customer Reviews (3)
Write a reviewBulk production often leads to economies of scale, making the CP protein more cost-effective for research budgets.
Manufacturers with the capacity for bulk production can offer CP protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.
Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using CP protein.
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