CPD

  • Official Full Name

    carboxypeptidase D
  • Overview

    The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
  • Synonyms

    CPD;carboxypeptidase D;gp180;Metallocarboxypeptidase D

Recombinant Proteins

  • Rat
  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • E.coli
  • Insect Cells
  • His
  • Avi
  • Fc
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CPD-1565R Recombinant Rat CPD Protein Mammalian Cells Rat His
CPD-3835M Recombinant Mouse CPD Protein Mammalian Cells Mouse His
CPD-1222R Recombinant Rat CPD Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
CPD-1222R-B Recombinant Rat CPD Protein Pre-coupled Magnetic Beads HEK293 Rat
CPD-1924M Recombinant Mouse CPD Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CPD-1924M-B Recombinant Mouse CPD Protein Pre-coupled Magnetic Beads HEK293 Mouse
CPD-2722H Recombinant Human CPD protein, His&Myc-tagged E.coli Human His&Myc 383-461aa
CPD-5899H Recombinant Human CPD protein, His&Myc-tagged Insect Cells Human His&Myc 383-461aa
CPD-5937H Recombinant Human CPD protein, hFc-Myc-tagged HEK293 Human Fc&Myc 383-461aa

    Involved Pathway

    CPD involved in several pathways and played different roles in them. We selected most pathways CPD participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Golgi Associated Vesicle Biogenesis PICALMA,PICALMB,SH3D19,PUM1,AP1S3A,AP1B1,NAPAB,AP1G1,TGOLN2,AP1S1
    Membrane Trafficking GJB5,TBC1D8B,SNX9B,EXOC8,AP4B1,PUM1,MIA3,PICALMA,NSFA,MYO1C
    Clathrin derived vesicle budding FTH1B,NAPAB,BLOC1S6,AP3S1,AP1B1,DTNBP1,PICALM,DNASE2,APPB,CNO
    trans-Golgi Network Vesicle Budding AP3S1,BLOC1S3,CLVS2,CNO,SNX9,PICALMB,PICALM,CLINT1,TFR1B,PUM1
    Vesicle-mediated transport TFR1B,STXBP3,GJA8,GJA4,SNX9A,SNF8,TCEAL4,DTNBP1,GJB4,PICALMB

    Protein Function

    CPD has several biochemical functions, for example, carboxypeptidase activity,hydrolase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPD itself. We selected most functions CPD had, and list some proteins which have the same functions with CPD. You can find most of the proteins on our site.

    Function Related Protein
    protein complex binding HSPD1,TULP3,PPP1R9B,MAPK8IP2,NDUFA9,LCK,LZTFL1,C8B,THRA,HTR2A
    peptidase activity Casp3,C6AST3,BAP1,F9A,ESPL1,USP12A,FAP,ZMPSTE24,AGBL4,CASP3A
    metal ion binding TPH1B,ACACA,MGAT4A,SMYD1,ZC3H8,ITK,ATP1A3A,PRKAA1,CYP2AA7,ZFP35
    carboxypeptidase activity PGCP,CPB1,AGBL1,CNDP1,CTSA,CPE,AGBL4,CPM,NAALAD2,CPA2
    protein phosphatase 2A binding IGBP1,SHC1,ENSAA,PPP2R4,ANKLE2,MAPT,PPME1,ENSA,TP53,STRN4
    metallocarboxypeptidase activity AGTPBP1,CPB1,PEPD,AGBL2,CPB2,CPZ,CPO,CPDB,CPA3,FOLH1
    zinc ion binding MSRB3,NR5A1A,OAS1,ADAMTS9,PHF20B,ADAMTSL3,CA4,RORCB,NR6A1A,THRA
    hydrolase activity PTPRQ,DPYSL5A,GPN3,SSH2B,REXO4,F9B,PL10,ATP8B1,EAR3,CES3A
    serine-type carboxypeptidase activity CPM,SCPEP1,PRCP,CPN1,DPP7,SENP2,CPVL,CPZ,CPDB,CPE

    Interacting Protein

    CPD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPD here. Most of them are supplied by our site. Hope this information will be useful for your research of CPD.

    Ankrd1;Ywhae;Clstn1

    Resources

    References

    • Guthrie, JW; Limmer, RT; et al. Simultaneous detection of ultraviolet B-induced DNA damage using capillary electrophoresis with laser-induced fluorescence. ANALYTICA CHIMICA ACTA 853:676-681(2015).
    • Pastor, M; Esquisabel, A; et al. Cellulose acetate phthalate microparticles containing Vibrio cholerae: steps toward an oral cholera vaccine. JOURNAL OF DRUG TARGETING 22:478-487(2014).

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