CPT1B

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CPT1B

Official Full Name carnitine palmitoyltransferase 1B (muscle)
Background The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
Synonyms CPT1B; carnitine palmitoyltransferase 1B (muscle); carnitine O-palmitoyltransferase 1, muscle isoform; CPT1 M; M CPT1; carnitine palmitoyltransferase I-like protein; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; CPTI; CPT1M; MCPT1; CPT
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPT1B-1455H Recombinant Human CPT1B protein, His & T7-tagged E.coli His/T7
    Human CPT1B-1819H Recombinant Human CPT1B Protein, GST-tagged Wheat Germ GST
    Human CPT1B-26102TH Recombinant Human CPT1B Wheat Germ N/A
    Human CPT1B-7299HCL Recombinant Human CPT1B 293 Cell Lysate HEK293 N/A
    Mouse CPT1B-3866M Recombinant Mouse CPT1B Protein Mammalian Cell His
    Cynomolgus Monkey CPT1B-420C Recombinant Cynomolgus CPT1B Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CPT1B-1011R Recombinant Rhesus monkey CPT1B Protein, His-tagged Mammalian Cell His
    Zebrafish CPT1B-1474Z Recombinant Zebrafish CPT1B Mammalian Cell His

    CPT1B involved in several pathways and played different roles in them. We selected most pathways CPT1B participated on our site, such as AMPK signaling, AMPK signaling pathway, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPT1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AMPK signaling CPT1A; INS-IGF2; EEF2; PPARGC1B; CPT1C; CAMKK2; ELAVL1; CPT1B; EIF4EBP1; ADRa1A
    AMPK signaling pathway IGF1R; HMGCR; RHEB; PPP2R5C; G6PC2; SREBF1; CCNA1; STRADA; PPP2R3A; PIK3CB
    Adipocytokine signaling pathway JAK2B; PTPN11A; ACSL1A; ADIPOQB; ACSL3B; LEP; PRKAA2; IRS4; ACSL5; ACSBG1
    FOXA2 and FOXA3 transcription factor networks CEBPA; TTR; CPT1C; KCNJ11; DLK1; CPT1A; UCP2; CPT1B; FOXA1; FOXF1
    Fatty Acid Beta Oxidation CPT2; SLC25A20; DECR1; ECI1; CRAT; CPT1B; CHKB; CPT1A
    Fatty acid degradation GCDHA; HADHAA; ACSL4A; CYP4A14; ACSBG1; ADH1C; ADH5; ACOX1; GCDH; ACSL5
    Fatty acid metabolism ACACA; ACSL1B; FASN; ACADVL; ACSBG1; ACSL1; FADS2; Scd1; HADHAA; ELOVL6
    Fatty acid, triacylglycerol, and ketone body metabolism ACOT13; CPT1B; MED22; SREBF2; MED9; THEM5; SLC25A1; MED15; CDK19; ELOVL1A

    CPT1B has several biochemical functions, for example, carnitine O-palmitoyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPT1B itself. We selected most functions CPT1B had, and list some proteins which have the same functions with CPT1B. You can find most of the proteins on our site.

    Function Related Protein
    carnitine O-palmitoyltransferase activity CPT2; CPT1C; CPT1A; CPT1B
    protein binding GNB2L1; RPS11; SHFM1; DOLK; TMEM115; NINJ2; TMPRSS2; ZWILCH; ERH; COPRS

    CPT1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPT1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CPT1B.

    C2orf57

    Gao, S; McMillan, RP; et al. Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin. DIABETES 63:3242-3252(2014).
    Gomez-Gomez, E; Rios-Martinez, ME; et al. Carnitine Palmitoyltransferase 1B 531K Allele Carriers Sustain a Higher Respiratory Quotient after Aerobic Exercise, but beta 3-Adrenoceptor 64R Allele Does Not Affect Lipolysis: A Human Model. PLOS ONE 9:-(2014).

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