CSTF3

  • Official Full Name

    cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa

  • Overview

    The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3 end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

  • Synonyms

    CSTF3;cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa;cleavage stimulation factor, 3 pre RNA, subunit 3, 77kD;cleavage stimulation factor subunit 3;CstF 77;CF-1 77 kDa subunit;CSTF 77 kDa subunit;cleavage stimulation factor 77 kDa subunit

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CSTF3-11652H Recombinant Human CSTF3, GST-tagged E.coli Human GST 1-103a.a.
CSTF3-1072R Recombinant Rhesus monkey CSTF3 Protein, His-tagged Mammalian Cells Rhesus macaque His
CSTF3-12288Z Recombinant Zebrafish CSTF3 Mammalian Cells Zebrafish His
CSTF3-1940C Recombinant Chicken CSTF3 Mammalian Cells Chicken His
CSTF3-2044H Recombinant Human CSTF3 Protein, GST-tagged Wheat Germ Human GST
CSTF3-7222HCL Recombinant Human CSTF3 293 Cell Lysate HEK293 Human Non
CSTF3-2253HF Recombinant Full Length Human CSTF3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 103 amino acids
Cstf3-2350M Recombinant Mouse Cstf3 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
CSTF3-897R Recombinant Rhesus Macaque CSTF3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
CSTF3-897R-B Recombinant Rhesus Macaque CSTF3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    CSTF3 involved in several pathways and played different roles in them. We selected most pathways CSTF3 participated on our site, such as Cleavage of Growing Transcript in the Termination Region,Gene Expression,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSTF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Processing of Capped Intronless Pre-mRNA CLP1,LSM11,LSM10,CSTF1,SLBP,PAPOLA,ZFP473,NUDT21,ZNF473,CSTF2
    Processing of Capped Intron-Containing Pre-mRNA PRPF8,HNRNPR,SRSF11,PDCD7,CLP1,DNAJC8,HNRPL,HNRNPF,U2AF2,CSTF1
    Processing of Intronless Pre-mRNAs CSTF2,NUDT21,CLP1,PAPOLA,CSTF1
    RNA Polymerase II Transcription CCNT2A,NELFE,SUPT16H,LSM11,LSM10,U2AF2,RNPS1,NUDT21,CSTF1,GM3258
    mRNA 3-end processing SRSF11,SFRS3A,CSTF2,NUDT21,CLP1
    Gene Expression HBXIP,SETB,ZNF671,ZNF643,ADAT2,ZNF157,ZNF777,NR2C2AP,ZNF776,SFRS3A
    RNA Polymerase II Transcription Termination CSTF1,SRSF11,ZNF473,CSTF2,LSM11,SLBP,THOC4,CLP1,RNPS1,U2AF2
    Cleavage of Growing Transcript in the Termination Region LSM11,THOC4,NUDT21,CSTF2,ZNF473,CSTF1,CLP1,SLBP,SRSF11,U2AF2

    Protein Function

    CSTF3 has several biochemical functions, for example, RNA binding,mRNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSTF3 itself. We selected most functions CSTF3 had, and list some proteins which have the same functions with CSTF3. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding RRP7A,MRPS21,RPL24,CDK13,ATXN2L,EXOSC8,CS,MTERF,NOC4L,EIF5A
    protein binding WNT3,OLIG1,RHPN1,ARHGEF4,BCL2L14,SIAH2,JAM2A,ADRA2A,RUSC2,BAG4
    mRNA binding D19BWG1357E,SSB,QKI,CPSF5,RPS13,RBFOX1,RBPMS2B,MECP2,QK,RBFOX1L
    RNA binding IMPDH2,U2AF2A,MBNL1,HNRNPH2,RBM20,KHDC3L,SUZ12,SMN1,ADAD1,ZMAT2

    Interacting Protein

    CSTF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSTF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSTF3.

    CDK4;VHL;IKBKE;emrR;15-deoxy-delta(12,14;ssrna_ug;NPM1;SNW1;RNPS1;FIP1L1;Myh9

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