CYP26C1

  • Official Full Name

    cytochrome P450, family 26, subfamily C, polypeptide 1

  • Overview

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33.

  • Synonyms

    CYP26C1;cytochrome P450, family 26, subfamily C, polypeptide 1;cytochrome P450 26C1;FLJ45301
Cat.# Product name Source (Host) Species Tag Protein Length Price
CYP26C1-2252H Recombinant Human CYP26C1 Protein, GST-tagged Wheat Germ Human GST
CYP26C1-3181Z Recombinant Zebrafish CYP26C1 Mammalian Cells Zebrafish His
Cyp26c1-2416M Recombinant Mouse Cyp26c1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
CYP26C1-2679H Recombinant Human CYP26C1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
CYP26C1-3391H Recombinant Human CYP26C1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc

    Involved Pathway

    CYP26C1 involved in several pathways and played different roles in them. We selected most pathways CYP26C1 participated on our site, such as Retinol metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP26C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Retinol metabolism UGT1A7C,UGT2A3,DHRS9,RDH10B,CYP3A65,RDH8A,PNPLA4,RDH8B,CYP2C18,UGT5G1
    Metabolic pathways POLE3,ADSSL,INPP1,RIMKLA,PLD1A,PLCG1,B3GNT5A,BAAT,CHSY1,HEXB

    Protein Function

    CYP26C1 has several biochemical functions, for example, heme binding,iron ion binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP26C1 itself. We selected most functions CYP26C1 had, and list some proteins which have the same functions with CYP26C1. You can find most of the proteins on our site.

    Function Related Protein
    monooxygenase activity CYP1C2,CYP2P10,CYP2A12,CYP2N13,CYP2C54,YWHAE1,CYP1A1,CYP3C4,CYP2B6,CYP2AA3
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen CYP2D10,CYP17A2,CYP27C1,CYP2AD6,CYP2AA8,CYP2C70,PLOD1A,CYP7A1A,CYP4F18,CYP2P6
    metal ion binding KDM2BA,TRIM59,ATF7,ZDHHC14,CLCA1,PRPSAP2,USP19,CD209C,TIMP2,TERT
    heme binding CYP2N13,PTGES2,CYGB,CYP2P6,HRG,HRG-1,FAM84B,CYP2K17,CYP2AA9,PTGESL
    oxidoreductase activity PYROXD1,DEGS2,UOX,PPM1NA,CYB561A3A,SDR16C5B,AKR1B7,CRYM,DAO.1,ALDH3A2B
    iron ion binding CYP3A5,CYP2K22,CYP46A1.4,CYP2A12,TPH2,BA1,SC4MOL,CYP2C55,CYP1B1,CYP2J6

    Interacting Protein

    CYP26C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP26C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP26C1.

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