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Official Full Name cytochrome P450, family 2, subfamily S, polypeptide 1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.
Synonyms CYP2S1; cytochrome P450, family 2, subfamily S, polypeptide 1; cytochrome P450, subfamily IIS, polypeptide 1; cytochrome P450 2S1; CYPIIS1; cytochrome P540, subfamily IIS, polypeptide 1; cytochrome P450 family member predicted from ESTs
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cyp2s1-2419M Recombinant Mouse Cyp2s1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CYP2S1-7108HCL Recombinant Human CYP2S1 293 Cell Lysate HEK293 N/A
    Mouse CYP2S1-4201M Recombinant Mouse CYP2S1 Protein Mammalian Cell His

    cyp2s1 involved in several pathways and played different roles in them. We selected most pathways cyp2s1 participated on our site, such as Biological oxidations, CYP2E1 reactions, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with cyp2s1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biological oxidations CYP19A1; CYP2K8; CYP4T8; ACY3.2; AKR1A1; CYP26A1; CYP21A2; CYP2D6; CYP2J2; CYP2C9
    CYP2E1 reactions CYP2C19; CYP2C9; CYP2A13; CYP2F1; CYP2C8; CYP2E1; CYP2A6; CYP2Y3; CYP2A7; CYP2D6
    Cytochrome P450 - arranged by substrate type CYP2F1; CYP27B1; CYP1A1; CYP21A2; CYP2K6; CYP2A7; CYP2K8; CYP11B2; CYP3A7-CYP3AP1; CYP2E1
    Metabolic pathways FH1; MOCS2; PGLS; PON1; GLUL; NDUFS4; ALDH3B1; TGDS; NDUFA4; POLR2E
    Metabolism of xenobiotics by cytochrome P450 CYP2S1; PRKRA; AKR1C4; ADH2-1; ADH2-2; AKR1C2; CYP2F1; GSTK1
    Miscellaneous substrates CYP4F22; CYP2W1; CYP3C4; CYP2K16; CYP2K22; CYP2U1; CYP2K17; CYP3C1; CYP2K8; CYP4B1
    Phase 1 - Functionalization of compounds CYP2K8; CYP3A7-CYP3AP1; ADH8B; CYP2A7; CYP46A1; CES1; CYP2K22; CYP2R1; CYP3A7; CYP2W1

    cyp2s1 has several biochemical functions, for example, arachidonic acid epoxygenase activity, aromatase activity, heme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cyp2s1 itself. We selected most functions cyp2s1 had, and list some proteins which have the same functions with cyp2s1. You can find most of the proteins on our site.

    Function Related Protein
    arachidonic acid epoxygenase activity CYP2AD3; CYP2A4; CYP2J2; CYP2A13; CYP2P9; CYP2A7; CYP2S1; CYP2P6; CYP2C50; CYP2C18
    aromatase activity CYP2C18; CYP2B19; CYP3A25; CYP1A2; CYP2C37; CYP3A5; CYP3A7; CYP2D26; FAM84B; CYP2D6
    heme binding CYP2AA2; CYP2B19; HBAA; CYGB1; HBB-Y; CYP2Y3; MPO; CYP2AA9; IDO2; BA1
    iron ion binding LEPRE1; HBQ1; CYP2C19; BA1; HBE; HBM; CYP11B2; CYP46A1.4; CYP1C1; CYP7B1
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen CYP2C19; CYP2AA1; CYP2K22; CYP2P6; CYP2X7; CYP2AA2; CYP2C54; CYP2P9; CYP2AA3; CYP2X9
    oxygen binding CYP26A1; CYP2AD3; CYP2C54; Adgb; HBE; CYP2X9; CYP2D6; CYP2AA9; HBQ1; CYP2X7
    protein binding LPP; GNG10; HER5; NRIP3; STX3; PTPRD; PFDN2; CAB39L; LTBP2; TUBGCP2
    steroid hydroxylase activity CYP2K16; CYP2X7; CYP2X10.2; CYP46A1.4; CYP2C38; CYP2A13; FAM84B; CYP2R1; CYP2AA12; CYP2A4

    cyp2s1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cyp2s1 here. Most of them are supplied by our site. Hope this information will be useful for your research of cyp2s1.


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