Recombinant Full Length Human CYP2S1 Protein, C-Flag-tagged

• Cat.No.: CYP2S1-1451HFL
• Product Overview: Recombinant Full Length Human CYP2S1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.6 kDa
• AA Sequence: MEATGTWALLLALALLLLLTLALSG TRARGHLPPGPTPLPLLGNLLQLRP GALYSGLMRLSKKYGPVFTI YLGPWRPVVVLVGQEAVREALGGQA EEFSGRGTVAMLEGTFDGHGVFFSN GERWRQLRKFTMLALRDLGM GKREGEELIQAEARCLVETFQGTEG RPFDPSLLLAQATSNVVCSLLFGLR FSYEDKEFQAVVRAAGGTLL GVSSQGGQTYEMFSWFLRPLPGPHK QLLHHVSTLAAFTVRQVQQHQGNLD ASGPARDLVDAFLLKMAQEE QNPGTEFTNKNMLMTVIYLLFAGTM TVSTTVGYTLLLLMKYPHVQKWVRE ELNRELGAGQAPSLGDRTRL PYTDAVLHEAQRLLALVPMGIPRTL MRTTRFRGYTLPQGTEVFPLLGSIL HDPNIFKHPEEFNPDRFLDA DGRFRKHEAFLPFSLGKRVCLGEGL AKAELFLFFTTILQAFSLESPCPPD TLSLKPTVSGLFNIPPAFQL
  QVRPTDLHSTTQTRTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Metabolism of xenobiotics by cytochrome P450

Gene Information

• Gene Name: CYP2S1 cytochrome P450 family 2 subfamily S member 1 [ Homo sapiens (human) ]
• Official Symbol: CYP2S1
• Synonyms: CYPIIS1
• Gene ID: 29785
• mRNA Refseq: NM_030622.8
• Protein Refseq: NP_085125.1
• MIM: 611529
• UniProt ID: Q96SQ9