cyp2u1

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cyp2u1

Official Full Name cytochrome P450, family 2, subfamily U, polypeptide 1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids.
Synonyms CYP2U1; cytochrome P450, family 2, subfamily U, polypeptide 1; cytochrome P450 2U1; CP2U1_HUMAN; CYP2U 1; EC 1.14.14.1; P450TEC
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP2U1-2270H Recombinant Human CYP2U1 Protein, GST-tagged Wheat Germ GST
    Human CYP2U1-435HCL Recombinant Human CYP2U1 cell lysate N/A
    Mouse CYP2U1-4203M Recombinant Mouse CYP2U1 Protein Mammalian Cell His
    Rat CYP2U1-1742R Recombinant Rat CYP2U1 Protein Mammalian Cell His
    Zebrafish CYP2U1-7322Z Recombinant Zebrafish CYP2U1 Mammalian Cell His

    cyp2u1 involved in several pathways and played different roles in them. We selected most pathways cyp2u1 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with cyp2u1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism FAAH2A; GPX6; CYP2AD2; CYP2U1; CYP4F3; DPEP2; CYP4A14; AWAT1; GPX1; CYP1A2
    Biological oxidations FAM84B; ADH7; CYP2AD6; COMT; SULT1C4; CYP4F11; CYP24A1; CYP27B1; CYP2AD3; CYP17A1
    Cytochrome P450 - arranged by substrate type CYP3A4; CYP4F11; CYP2C9; CYP46A1; CYP2K6; CYP3A7-CYP3AP1; CYP3A7; CYP4F12; CYP2S1; CYP2J2
    Metabolic pathways ST6GALNAC5; NT5C2B; GLCE; COX15; B4GALT4; MOGS; NT5C1B-RDH14; NDUFAB1A; MTMR14; HEXB
    Metabolism CYGB; AKR1C6; ACOT9.1; SLC6A7; SLC5A4; CYP3A7; FTCD; CYP2K16; NAALAD2; NUDT15
    Metabolism of lipids and lipoproteins AKR1C4; MED23; DGAT1B; FAM213B; PPP1R2; CETP; ARSI; DPEP2; MED6; CLPS
    Miscellaneous substrates CYP3C1; CYP2K16; CYP2U1; CYP2K8; CYP2K6; CYP4F22; CYP3C4; CYP2K19; CYP2S1; CYP2K22
    Phase 1 - Functionalization of compounds CYP2AD6; CYP2F1; CYP2W1; CYP26A1; CYP3A7; CYP2R1; CYP2S1; CYP2AD3; CYP8B2; CYP4F12

    cyp2u1 has several biochemical functions, for example, aromatase activity, heme binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cyp2u1 itself. We selected most functions cyp2u1 had, and list some proteins which have the same functions with cyp2u1. You can find most of the proteins on our site.

    Function Related Protein
    aromatase activity CYP2D10; CYP3A7; CYP2A7; CYP2B19; CYP2J2; CYP2F1; CYP2C37; CYP2J5; CYP2C39; CYP1B1
    heme binding CYP7B1; CYP2C50; CYP11C1; CYCS; CYP2AA1; CYP2C39; IRGM1; CYP4B1; FA2H; HBBE3
    iron ion binding CYP1C2; CYP2P8; CYP2C8; CYP26B1; HBBE2; CYP2N13; Agmo; CYP3A43; JHDM1D; CYP2A12
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen CYP2C18; CYP2A6; CYP2C8; CYP2C37; CYP2C9; CYP2AA7; CYP1A2; CYP1A; CYP2B19; CYP2K17
    oxygen binding TH; HBA2; CYP2K22; CYP2J6; HBBE3; TDO2; CYP2W1; CYP2C70; CBS; CYP2J2
    steroid hydroxylase activity CYP2C38; CYP46A1.3; CYP2AA9; CYP46A1.2; CYP2P6; CYP21A2; CYP2D6; CYP2C19; CYP2K16; CYP2A6

    cyp2u1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cyp2u1 here. Most of them are supplied by our site. Hope this information will be useful for your research of cyp2u1.

    MYC

    Lopez-Vicario, C; Alcaraz-Quiles, J; et al. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:536-541(2015).
    Wortmann, SB; Espeel, M; et al. Inborn errors of metabolism in the biosynthesis and remodelling of phospholipids. JOURNAL OF INHERITED METABOLIC DISEASE 38:99-110(2015).

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