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Official Full Name cytochrome P450, family 4, subfamily A, polypeptide 11
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008]
Synonyms CYP4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; CP4Y; CYP4A2; CYP4AII; cytochrome P450 4A11; CYPIVA11; P450HL-omega; 20-HETE synthase; alkane-1 monooxygenase; cytochrome P450HL-omega; cytochrome P-450HK-omega; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase; 20-hydroxyeicosatetraenoic acid synthase; cytochrome P450, subfamily IVA, polypeptide 11;
    • Species :
    • Cynomolgus Monkey
    • Human
    • Source :
    • E. coli
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP4A11-11787H Recombinant Human CYP4A11, GST-tagged E.coli GST
    Human CYP4A11-2280H Recombinant Human CYP4A11 Protein, GST-tagged Wheat Germ GST
    Human CYP4A11-26692TH Recombinant Human CYP4A11 Wheat Germ N/A
    Human CYP4A11-439HCL Recombinant Human CYP4A11 cell lysate N/A
    Human CYP4A11-73H Recombinant Human CYP4A11 Protein E.coli
    Human CYP4A11-84H Recombinant Human CYP4A11 Protein E. coli
    Cynomolgus Monkey CYP4A11-445C Recombinant Cynomolgus CYP4A11 Protein, His-tagged Mammalian Cell His

    cyp4a11 involved in several pathways and played different roles in them. We selected most pathways cyp4a11 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with cyp4a11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP1B1; HPGDS; CYP2J2; FAAH2A; PTGES3A; CYP2B6; PLA2G4C; ALOX5A; CYP1A1; CYP4A11
    Biological oxidations CYP2AD3; CYP2A13; ABHD10; CYP46A1; AADAC; CYP2V1; CYP2E1; ADH7; CYP2C9; AKR1A1
    Cytochrome P450 - arranged by substrate type FDXR; CYP1B1; CYP3C4; CYP17A1; CYP2D6; CYP2K19; CYP2K8; CYP4F11; CYP27B1; CYP19A1
    Eicosanoids CYP4A11; CYP4B1; CYP4F12; CYP4F22; CYP4F11
    Fatty Acid Omega Oxidation CYP4A11; CYP2D6; ADH4; ADH6; ADH7; CYP2E1; ADH1B; CYP1A1; ADH1C; CYP2A6
    Fatty acid degradation CYP4A14; ACAA1A; HADH; HADHAB; ACSBG2; ACAT2; ACADVL; HADHB; CYP4A12A; PECI
    Fatty acid, triacylglycerol, and ketone body metabolism SLC25A1A; SREBF2; MED19; CCNC; ACAD11; MED15; CYP4A11; ACOT11A; ACOT13; ACOT9
    Fatty acids CYP2J2; CYP2A7; CYP4A11; CYP2AD6; CYP4T8; CYP2D6; CYP4F12; CYP2B6; CYP2V1; CYP4F22

    cyp4a11 has several biochemical functions, for example, alkane 1-monooxygenase activity, arachidonic acid epoxygenase activity, heme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cyp4a11 itself. We selected most functions cyp4a11 had, and list some proteins which have the same functions with cyp4a11. You can find most of the proteins on our site.

    Function Related Protein
    alkane 1-monooxygenase activity CYP4A12A; CYP4F18; CYP4F2; CYP4F12; CYP4A11; CYP4A14; CYP4A10
    arachidonic acid epoxygenase activity CYP2AD2; CYP2A7; CYP2AA12; CYP2P7; CYP2P6; CYP2P9; CYP4F12; CYP2AA7; CYP2A13; CYP2C54
    heme binding CYP4F18; CYP46A1; CYP2W1; CYP4V7; DGCR8; CYP1A2; HRG-1; CYP46A1.1; HBA1; CYP8B3
    iron ion binding HBD; HBAA1; NOS2; FA2H; ALOX15; AOX1; ACO2; CYP2K17; P4HA2; PPEF1
    leukotriene-B4 20-monooxygenase activity CYP4F2; CYP4F14; CYP4F18; CYP4A11; CYP4F3; CYP4A10; CYP4F12

    cyp4a11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cyp4a11 here. Most of them are supplied by our site. Hope this information will be useful for your research of cyp4a11.


    Uehara, S; Murayama, N; et al. Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine. XENOBIOTICA 45:124-130(2015).
    Chen, L; Ackerman, R; et al. 20-HETE Regulates the Angiogenic Functions of Human Endothelial Progenitor Cells and Contributes to Angiogenesis In Vivo. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 348:442-451(2014).

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