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CYP4F11

  • Official Full Name

    cytochrome P450, family 4, subfamily F, polypeptide 11

  • Overview

    This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    CYP4F11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; cytochrome P450 4F11; CYPIVF11;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Homo sapiens (Human)
  • Human
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • His|SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYP4F11-11789H Recombinant Human CYP4F11, GST-tagged E.coli GST C-term-350a.a.
Human CYP4F11-2282H Recombinant Human CYP4F11 Protein, GST-tagged Wheat Germ GST
Human CYP4F11-7103HCL Recombinant Human CYP4F11 293 Cell Lysate HEK293 N/A
Human CYP4F11-2442HF Recombinant Full Length Human CYP4F11 Protein, GST-tagged In Vitro Cell Free System GST 524 amino acids
Human CYP4F11-1130H Recombinant Human CYP4F11 Protein (38-524 aa), His-SUMO-tagged E.coli His/SUMO 38-524 aa
Human CYP4F11-5080H Recombinant Human CYP4F11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Homo sapiens (Human) RFL17054HF Recombinant Full Length Human Cytochrome P450 4F11(Cyp4F11) Protein, His-Tagged E.coli expression system His Full Length (1-524)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CYP4F11 involved in several pathways and played different roles in them. We selected most pathways CYP4F11 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4F11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arachidonic acid metabolismAKR1C6;PTGR1;GPX5;CYP2C70;DPEP1;TBXAS1;CYP2AD3;PTGDS;CYP2B6
Biological oxidationsCYP2V1;UGT1B2;SLC35D1A;CES1;ADH1A;SULT2ST2;CYP2D6;CYP24A1;SULT4A1
Cytochrome P450 - arranged by substrate typeCYP2K17;CYP7A1;CYP3A7;CYP2K22;CYP2K8;CYP27A1;CYP1B1;CYP2V1;CYP8B2
EicosanoidsCYP4B1;CYP4F11;CYP4F22;CYP4F12;CYP4A11
Fatty acidsCYP2V1;CYP2D6;CYP2N13;CYP2AD2;CYP2J2;CYP2AD3;CYP4A11;CYP2A13;CYP4F12
MetabolismCYP2V1;CDK19;APOF;COQ6;CPTP;ETFDH;SULT4A1;ADH8B;PTGDSA
Metabolism of lipids and lipoproteinsSCP2B;ALOX5AP;SLCO1B1;DECR1;GLTPD1;CYP46A1;ACOT10;AKR1C2;FABP11B
Miscellaneous substratesCYP2K22;CYP2K18;CYP2K17;CYP2K16;CYP3C1;CYP4F22;CYP2S1;CYP4B1;CYP2K6

CYP4F11 has several biochemical functions, for example, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4F11 itself. We selected most functions CYP4F11 had, and list some proteins which have the same functions with CYP4F11. You can find most of the proteins on our site.

Function Related Protein
heme bindingCYP2P10;CYP2K18;CYP11B2;NR1D1;CAT;HBB-BH1;CYP27B1;CYP2AA2;IDO1
iron ion bindingOGFOD2;EGLN3;CYP2C70;AOX1;CYP51;LTF;CYP8B1;CYP4B1;CYP2X9
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygenNDOR1;CYP11C1;CYP4F18;CYP4F2;MICAL1;CYP11B1;COQ6;CYP11A1;POR

CYP4F11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4F11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4F11.

POT1

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