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CYP4V2

  • Official Full Name

    cytochrome P450, family 4, subfamily V, polypeptide 2

  • Overview

    This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy.
  • Synonyms

    CYP4V2; cytochrome P450, family 4, subfamily V, polypeptide 2; cytochrome P450 4V2; CYP4AH1; BCD; CYP4V 2; Retina CYP4V2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYP4V2-2287H Recombinant Human CYP4V2 Protein, GST-tagged Wheat Germ GST
Human CYP4V2-440HCL Recombinant Human CYP4V2 cell lysate N/A
Human CYP4V2-2462HF Recombinant Full Length Human CYP4V2 Protein, GST-tagged In Vitro Cell Free System GST 525 amino acids
Homo sapiens (Human) RFL36768HF Recombinant Full Length Human Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged E.coli expression system His Full Length (1-525)
Mus musculus (Mouse) RFL16376MF Recombinant Full Length Mouse Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged E.coli expression system His Full Length (1-525)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL34569PF Recombinant Full Length Pongo Abelii Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged E.coli expression system His Full Length (1-525)
Rattus norvegicus (Rat) RFL768RF Recombinant Full Length Rat Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged E.coli expression system His Full Length (1-525)
Rhesus Macaque CYP4V2-1165R Recombinant Rhesus monkey CYP4V2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CYP4V2-990R-B Recombinant Rhesus Macaque CYP4V2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CYP4V2-990R Recombinant Rhesus Macaque CYP4V2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CYP4V2-1179C Recombinant Chicken CYP4V2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CYP4V2 Related Articles

CYP4V2 involved in several pathways and played different roles in them. We selected most pathways CYP4V2 participated on our site, such as cytochrome P450, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4V2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cytochrome P450CYP4Z1;CYP20A1;CYB5R3;CYB5A;CYB5B;CYP2W1;POR;CYP4F12;CYP2A7
metapathway biotransformationSULT4A1;NAA20;GAL3ST3;NAT8B;CYP4Z1;CEACAM21;HS3ST6;NAA50;CHST8

CYP4V2 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4V2 itself. We selected most functions CYP4V2 had, and list some proteins which have the same functions with CYP4V2. You can find most of the proteins on our site.

Function Related Protein
heme bindingCYB5A;CYP1A;HBZ;HBA-X;CYP2AA9;CYP2AA6;MFSD7C;SDHDA;FAM84B
iron ion bindingCYP2X7;CYP3C1L2;EGLN1;CYP2E1;CYP2AD2;PLOD1A;CYP2P10;CYP2S1;CYGB1
monooxygenase activityCYP2K18;CYP2P10;CYP4V8;CYP4A14;CYP2AA7;CYP1C1;CYP2Y3;CYP3A25;BCMO1
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenCYP2AA1;CYP2C70;CYP2X8;CYP2AA7;P4HA1B;CYP4T8;CYP2X10.2;CYP8B1;CYP2AA12

CYP4V2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4V2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4V2.

ZNF420

Efstathiou, E; Titus, M; et al. Molecular Characterization of Enzalutamide-treated Bone Metastatic Castration-resistant Prostate Cancer. EUROPEAN UROLOGY 67:53-60(2015).
Takahashi, K; Kishimoto, Y; et al. Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1840:2289-2298(2014).
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