DDAH2
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Official Full Name
Dimethylarginine Dimethylaminohydrolase 2
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Overview
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. -
Synonyms
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; dime-thylarginine dimethylaminohydrolase 2; DDAH-2; DDAH; DDAH2; protein G6a; S-phase protein; dimethylargininase-2; NG30; G6a; dimethylarginine dimethylaminohydrolase II; NG-dimethylarginine dimethylamino hydrolase homolog; dimethylarginine dimethylaminohydrolase 2; OT-THUMP00000029307; OTTHUMP00000029308; OT-THUMP00000029310; OTTHUMP00000174406; OT-THUMP00000174488; OTTHUMP00000174489; EC 3.5.3.18; alternative name: NG30, G6a;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
DDAH2 involved in several pathways and played different roles in them. We selected most pathways DDAH2 participated on our site, such as Metabolism, Metabolism of nitric oxide, eNOS activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDAH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | DPYD;NDUFAF5;KCNJ11;TM9SF1;DHODH;CYP2AD2;LYPLA1;CTH;ADSSL1 |
| Metabolism of nitric oxide | DDAH1;ZDHHC21;SPRB;GCHFR;LYPLA1;CYGB;CYGB1;NOSIP;NOSTRIN |
| eNOS activation | ZDHHC21;DDAH2;LYPLA1;CYGB2;CYGB;CYGB1;DDAH1 |
| eNOS activation and regulation | NOSTRIN;ZDHHC21;DDAH2;CYGB;DDAH1;CYGB2;SPRB;LYPLA1;GCHFR |
DDAH2 has several biochemical functions, for example, amino acid binding, catalytic activity, dimethylargininase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDAH2 itself. We selected most functions DDAH2 had, and list some proteins which have the same functions with DDAH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| amino acid binding | ASS1;TDO2;GOT2;GCHFR;TPH1B;OTC;SHMT2;AARS;AARS2 |
| catalytic activity | GMPR2;PPM1LB;ISOC2B;PHKB;NRD1B;CKMT1;PCYT1AA;MOXD2;ECHDC3 |
| dimethylargininase activity | DDAH2;DDAH1 |
| protein binding | HSPA2;NR1H3;MYLK2;MYL2;RAD9A;APEH;RAB38;LAT2;GNA13 |
DDAH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDAH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDAH2.
TRIP13; TNFSF11; RPS6KA5; GADD45G; TK1; ATP1B1; CDK4; RCC1; ANXA7; CDKN1A; RAP1B; STK3; PIN1; RPS6KA1; TSC22D1; SMN1; CDC73; MKNK1
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