Recombinant Human DDAH2, His-tagged

• Cat.No.: DDAH2-26260TH
• Product Overview: Recombinant fragment, corresponding to amino acids 71-261 of Human DDAH2 with N terminal His tag; MWt 22kDa.

Specification

• Description: This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.
• Form: Lyophilised:Reconstitute with 53 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: LGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDL GLRIVEIGDENATLDGTDVLFTGREFFVGLSKWTNHRG AEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVA GSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLR PGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVS
• Sequence Similarities: Belongs to the DDAH family.

Gene Information

• Gene Name: DDAH2 dimethylarginine dimethylaminohydrolase 2 [ Homo sapiens ]
• Official Symbol: DDAH2
• Synonyms: DDAH2; dimethylarginine dimethylaminohydrolase 2; N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
• Gene ID: 23564
• mRNA Refseq: NM_013974
• Protein Refseq: NP_039268
• MIM: 604744
• Uniprot ID: O95865
• Chromosome Location: 6p21
• Function: amino acid binding; catalytic activity; dimethylargininase activity; hydrolase activity; protein binding