DDIT4

  • Official Full Name

    DNA-damage-inducible transcript 4

  • Overview

    Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.

  • Synonyms

    DDIT4;DNA-damage-inducible transcript 4;DNA damage-inducible transcript 4 protein;Dig2;FLJ20500;HIF 1 responsive RTP801;REDD 1;REDD1;RTP801;HIF-1 responsive protein RTP801;HIF-1 responsive RTP801 (RTP801);protein regulated in development and DN

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • DDK
  • Myc
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
REDD1-2245H Recombinant Human REDD1 protein E.coli Human GST 1 - 232 aa
DDIT4-10459Z Recombinant Zebrafish DDIT4 Mammalian Cells Zebrafish His
DDIT4-1207R Recombinant Rhesus monkey DDIT4 Protein, His-tagged Mammalian Cells Rhesus macaque His
DDIT4-1811R Recombinant Rat DDIT4 Protein Mammalian Cells Rat His
DDIT4-214H Recombinant Human DDIT4 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
DDIT4-2445H Recombinant Human DDIT4 Protein, GST-tagged Wheat Germ Human GST
DDIT4-28311TH Recombinant Human DDIT4 E.coli Human Non Full L. 1-232 a.a.
DDIT4-3433H Recombinant Full Length Human DDIT4 protein, His-tagged E.coli Human His Full L. 1-232 a.a.
DDIT4-7026HCL Recombinant Human DDIT4 293 Cell Lysate HEK293 Human Non
DDIT4-1032R Recombinant Rhesus Macaque DDIT4 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
DDIT4-1032R-B Recombinant Rhesus Macaque DDIT4 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
DDIT4-1469R Recombinant Rat DDIT4 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
DDIT4-1469R-B Recombinant Rat DDIT4 Protein Pre-coupled Magnetic Beads HEK293 Rat
DDIT4-2451HF Recombinant Full Length Human DDIT4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 232 amino acids
Ddit4-2493M Recombinant Mouse Ddit4 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    DDIT4 involved in several pathways and played different roles in them. We selected most pathways DDIT4 participated on our site, such as mTOR signaling pathway,PIK-Akt signaling pathway,MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDIT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MicroRNAs in cancer TNXB,NOTCH3,ABCC1,PTEN,MARCKS,SLC45A3,CCNG1,BMF,STMN1,KRAS
    mTOR signaling pathway PTENA,EIF4E2RS1,INS1,PIK3CD,RB1CC1,EIF4E1B,TSC1,TSC2,RPS6KA6,RRN3
    PIK-Akt signaling pathway VWF,INS2,IFNA7,NRAS,ITGA2B,COL6A5,GNG10,MTOR,Reln,IFNA10

    Protein Function

    DDIT4 has several biochemical functions, for example, 14-3-3 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDIT4 itself. We selected most functions DDIT4 had, and list some proteins which have the same functions with DDIT4. You can find most of the proteins on our site.

    Function Related Protein
    14-3-3 protein binding ARRB2,AKT1,PRKCE,HDAC7A,YWHAQ,AANAT,RPTOR,HDAC7,KCNH1,SRPK2

    Interacting Protein

    DDIT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDIT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDIT4.

    DDB1;BTRC;PDPK1;HSPA4;RIF1;q8czf9_yerpe;UBC;PLCG1;YWHAZ;CUL4A

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