Recombinant Human DDX6 protein, GST-tagged

• Cat.No.: DDX6-28328TH
• Product Overview: Recombinant Human DDX6(1 a.a. - 483 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 78.87 kDa
• AA Sequence: MSTARTENPVIMGLSSQNGQLRGPV KPTGGPGGGGTQTQQQMNQLKNTNT INNGTQQQAQSMTTTIKPGDDWKKT LKLPPKDLRIKTSDVTSTKGNEFED YCLKRELLMGIFEMGWEKPSPIQEE SIPIALSGRDILARAKNGTGKSGAY LIPLLERLDLKKDNIQAMVIVPTRE LALQVSQICIQVSKHMGGAKVMATT GGTNLRDDIMRLDDTVHVVIATPGR ILDLIKKGVAKVDHVQMIVLDEADK LLSQDFVQIMEDIILTLPKNRQILL YSATFPLSVQKFMNSHLQKPYEINL MEELTLKGVTQYYAYVTERQKVHCL NTLFSRLQINQSIIFCNSSQRVELL AKKISQLGYSCFYIHAKMRQEHRNR VFHDFRNGLCRNLVCTDLFTRGIDI QAVNVVINFDFPKLAETYLHRIGRS GRFGHLGLAINLITYDDRFNLKSIE EQLGTEIKPIPSNIDKSLYVAEYHS EPVEDEKP
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 [ Homo sapiens ]
• Official Symbol: DDX6
• Synonyms: DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); P54; HLR2; FLJ36338
• Gene ID: 1656
• mRNA Refseq: NM_001257191
• Protein Refseq: NP_001244120
• MIM: 600326
• UniProt ID: P26196
• Chromosome Location: 11q23.3
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Decapping complex, organism-specific biosystem; Decapping complex, conserved biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; mRNA Decay by 5 to 3 Exoribonuclease, organism-specific biosystem