DZIP3
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Official Full Name
DAZ interacting protein 3, zinc finger -
Synonyms
DZIP3;DAZ interacting protein 3, zinc finger;E3 ubiquitin-protein ligase DZIP3;hRUL138;human RNA binding ubiquitin ligase of 138 kDa;PPP1R66;protein phosphatase 1;regulatory subunit 66;UURF2 ubiquitin ligase;DAZ-interacting protein 3;zinc finger
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DZIP3-3001H | Recombinant Human DZIP3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DZIP3-6744HCL | Recombinant Human DZIP3 293 Cell Lysate | HEK293 | Human | Non |
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| DZIP3-4105HF | Recombinant Full Length Human DZIP3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 1120 amino acids |
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Involved Pathway
DZIP3 involved in several pathways and played different roles in them. We selected most pathways DZIP3 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DZIP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | RNF123,DYNC1H1,KLRG1,CLEC2G,ITPR2,SIGLEC7,NRG3,AP1M2,UBE2U,PJA2 |
| Antigen processing: Ubiquitination & | UFL1,MKRN1,ASB4,DTX3L,RNF138,TRIM11,RNF14,FBXO44,ASB7,LRR1 |
| presentation | BLMH,VPRBP,UBE2L6,WWP1,CD207,DTX3L,ATG7,WSB1,FBXO3,FBXO17 |
| Proteasome degradation | WSB1,TRAF7,RNF182,ATG7,TRIM39,ASB9,UFL1,UBA5,KLHL20,ASB11 |
| Immune System | OSBPL1A,PANX1A,IL1RN,TXNIP,CLEC2G,CD300LB,KLRB1A,EDA,GBP1,KLRB1F |
| Class I MHC mediated antigen processing & | FCGR1B,GAN,ASB8,HUWE1,KLHL21,DTX3L,LRR1,ASB13,TRIM9,FBXO17 |
Protein Function
DZIP3 has several biochemical functions, for example, RNA binding,ligase activity,phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DZIP3 itself. We selected most functions DZIP3 had, and list some proteins which have the same functions with DZIP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatase binding | DLG1,ELFN1,SYTL2,PPP1R26,PPARA,TRPC4AP,CNST,PPP1R36,TSC2,PPP1R37 |
| ubiquitin-protein transferase activity | RNF135,CBLL1,CNOT4B,TRAF4B,FBXO9,NEDD4L,RCHY1,KLHL20,PEX2,FBXL14B |
| RNA binding | BOLL,HNRNPM,MRPL23,EXOSC5,RPL26,EXOSC1,RPL39L,RPL6,HNRNPU,ENDOU |
| polyubiquitin binding | THRSP,TNIP2,RAD18,ZFAND6,BRE,DNAJB2,UBQLN4,PSMD4B,FAM175B,BRCC3 |
| protein binding | PAGE1,MRPL23,PAN3,ATP6V1F,EIF3G,ACVR2A,KHDC1B,ZCCHC10,PRPSAP1,ECD |
| poly(A) RNA binding | NOM1,RRP8,LIN28B,RARS2,RRP7A,FASTKD2,TRA2B,LARP2,PWP2,NOL6 |
| zinc ion binding | RORAA,GCM1,ZNF257,USP45,RNF133,CIZ1,LIMD2,HNF4G,MARCH6,JUB |
| ligase activity | CDC34A,PJA2,MEX3C,ZNRF3,UBE2L3B,PDZRN3,SIAH2L,TRIM50,RNF170,UBE4B |
| ubiquitin protein ligase activity | ITCH,FANCL,CMTM2A,UBE2C,RNF139,ZNRF1,CDC34,TRIM11,TRIP12,MED10 |
Interacting Protein
DZIP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DZIP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DZIP3.
ARHGAP32;ZNF24;HNRNPF;GTF2H2C;ZNF765;ZCCHC10;CEP63
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