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EEF1A2

  • Official Full Name

    eukaryotic translation elongation factor 1 alpha 2

  • Overview

    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
  • Synonyms

    EEF1A2; eukaryotic translation elongation factor 1 alpha 2; HS1; STN; EF1A; STNL; EEF1AL; EF-1-alpha-2; elongation factor 1-alpha 2; statin-S1; eukaryotic elongation factor 1 A-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Fc
  • Avi
  • Non
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EEF1A2-3061H Recombinant Human EEF1A2, T7-tagged E.coli T7 1-463
Human EEF1A2-12289H Recombinant Human EEF1A2 protein, GST-tagged E.coli GST 109-463 aa
Human EEF1A2-3067H Recombinant Human EEF1A2 Protein, GST-tagged Wheat Germ GST
Human EEF1A2-242HCL Recombinant Human EEF1A2 lysate HEK293 Non
Human EEF1A2-4206HF Recombinant Full Length Human EEF1A2 Protein, GST-tagged In Vitro Cell Free System GST 463 amino acids
Human EEF1A2-12290H Recombinant Human EEF1A2 protein, His-tagged E.coli His Gly213~Lys463
Mouse EEF1A2-4999M Recombinant Mouse EEF1A2 Protein Mammalian Cell His
Mouse EEF1A2-2646M Recombinant Mouse EEF1A2 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Mouse EEF1A2-2646M-B Recombinant Mouse EEF1A2 Protein Pre-coupled Magnetic Beads HEK293
Rat EEF1A2-2014R Recombinant Rat EEF1A2 Protein Mammalian Cell His
Rat EEF1A2-1671R Recombinant Rat EEF1A2 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Rat EEF1A2-1671R-B Recombinant Rat EEF1A2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EEF1A2-515Z Recombinant Zebrafish EEF1A2 Mammalian Cell His
Chicken EEF1A2-3258C Recombinant Chicken EEF1A2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

EEF1A2 involved in several pathways and played different roles in them. We selected most pathways EEF1A2 participated on our site, such as Eukaryotic Translation Elongation, Gene Expression, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEF1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Eukaryotic Translation ElongationRPL35;EEF2;EEF1A1;EEF1G;EEF1D;EEF1B2;EEF1A2
Gene ExpressionZFP473;SAP18;ZNF485;TAF1C;SSRP1;SLBP;ZNF200;ZNF70;ZNF37A
LegionellosisCASP9;HSPA8;CR1;NAIP7;CD14;Casp3;IL12A;CYCS;IL1B
Metabolism of proteinsODAM;GALNTL2;TGFBI;IGFBP6B;PAPPA;IGFBP2A;NAT8B;GALNTL5;EIF2B1
RNA transportUPF1;EIF4BA;EIF3HA;XPO1;EIF3C;STRAP;PABPC5;KPNB1;POP1
TranslationEIF5;EEF1G;EEF1A2;APEH;EEF1B2;EIF2B1;EEF1D
Translation FactorsEIF4EBP2;EEF1G;EEF1B2;EIF2B1;EIF5A;EEF1A2;EIF1;EEF2B;EEF1D

EEF1A2 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEF1A2 itself. We selected most functions EEF1A2 had, and list some proteins which have the same functions with EEF1A2. You can find most of the proteins on our site.

Function Related Protein
GTP bindingRASD2;RAB11BA;EIF5;MRAS;PCK1;ERAS;MFN1;RAB35B;GNL1
GTPase activitySRPR;RAB6C;RAB14;RALBA;GNAI1;RAB39BA;GNAT3;NKIRAS1;TUBB1
protein bindingCX3CL1;KLF13;FBXO11;ZBED4;TBX15;VCL;TIMELESS;SNRPA1;KL
protein kinase bindingSTAP1;IFNAR2;DNAJC3;LAT;ITGB1BP1;DVL1;PRKAB1;DBF4B;GATA6
translation elongation factor activityEEFSEC;GFM1;EEF1G;EEF1A1;EEF2B;EEF1A1L2;EEF1DA;TUFM;EEF2
translation factor activity, RNA bindingEIF4G2;CPEB3;EIF4A1;CPEB4;GTF2H3;EIF1;EEF1D;CPEB1;EIF4E2

EEF1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEF1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEF1A2.

ABTB1; NFKB2; CHUK; TNFRSF1B; EEF1B2; VARS; EEF1D; MAP3K8; NFKB2; RELA; TRAF2; MAP3K1; TRADD; LRRK2; MAP3K3; TAB2; TRAF6; RIPK3

Research Area

Related articles

Chen, CY; Fang, HY; et al. Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti-apoptotic activity in lung adenocarcinoma cells. CANCER SCIENCE 102:1582-1589(2011).
Piazzi, M; Bavelloni, A; et al. eEF1A Phosphorylation in the Nucleus of Insulin-stimulated C2C12 Myoblasts SER53 IS A NOVEL SUBSTRATE FOR PROTEIN KINASE C beta I. MOLECULAR & CELLULAR PROTEOMICS 9:-(2010).
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