eftud2 Protein, elongation factor Tu GTP binding domain containing 2

eftud2

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eftud2

Official Full Name elongation factor Tu GTP binding domain containing 2
Background 116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene.
Synonyms EFTUD2; elongation factor Tu GTP binding domain containing 2; 116 kDa U5 small nuclear ribonucleoprotein component; Snrp116; Snu114; U5 snRNP specific protein; 116 kD; U5 116KD; hSNU114; U5-116 kDa; SNU114 homolog; U5 snRNP specific protein, 116 kD; U5 sn
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EFTUD2-3110H Recombinant Human EFTUD2 Protein, GST-tagged Wheat Germ GST
    Human EFTUD2-6698HCL Recombinant Human EFTUD2 293 Cell Lysate HEK293 N/A
    Chicken EFTUD2-3147C Recombinant Chicken EFTUD2 Mammalian Cell His
    Zebrafish EFTUD2-10802Z Recombinant Zebrafish EFTUD2 Mammalian Cell His

    eftud2 involved in several pathways and played different roles in them. We selected most pathways eftud2 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with eftud2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome USP39; SRSF1A; SNRPG; SRSF10; PRPF6; HNRPKL; PUF60A; RBMX; HNRNPA1A; SRSF6

    eftud2 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by eftud2 itself. We selected most functions eftud2 had, and list some proteins which have the same functions with eftud2. You can find most of the proteins on our site.

    Function Related Protein
    GTP binding TUBA8L2; OPA1; RAB22A; MFN1; MXB; RAB11A; DNM3A; RHOT2; MOCS1; TUBB2
    GTPase activity RAP1B; GNAI1; RAB6B; DDX3X; RALAA; EFTUD2; GNAT3; GEM; TUBA2; RAB7A
    poly(A) RNA binding NPM3; RPUSD3; STAU2; UTP11L; NONO; DDX5; EIF2C3; RSL24D1; DMGDH; RPS4Y1
    protein binding NCS1; THSD4; C1QTNF6; CNKSR3; ANXA5; SERPINE1; ACYP2; SLC3A1; TDRD7; SERPINB1A
    NOT translation elongation factor activity EFTUD2; GFM2

    eftud2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with eftud2 here. Most of them are supplied by our site. Hope this information will be useful for your research of eftud2.

    MYC; SNRNP40; SNW1; PRPF8; HSPB1; IK; SF3B4; DFFA; PTP4A3

    Sato, N; Maeda, M; et al. Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. CANCER MEDICINE 4:268-277(2015).
    Gandomi, SK; Parra, M; et al. Array-CGH is an effective first-tier diagnostic test for EFTUD2-associated congenital mandibulofacial dysostosis with microcephaly. CLINICAL GENETICS 87:80-84(2015).

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