| Description : |
This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
109.5 kDa |
| AA Sequence : |
MDTDLYDEFGNYIGPELDSDEDDDE LGRETKDLDEMDDDDDDDDVGDHDD DHPGMEVVLHEDKKYYPTAEEVYGP EVETIVQEEDTQPLTEPIIKPVKTK KFTLMEQTLPVTVYEMDFLADLMDN SELIRNVTLCGHLHHGKTCFVDCLI EQTHPEIRKRYDQDLCYTDILFTEQ ERGVGIKSTPVTVVLPDTKGKSYLF NIMDTPGHVNFSDEVTAGLRISDGV VLFIDAAEGVMLNTERLIKHAVQER LAVTVCINKIDRLILELKLPPTDAY YKLRHIVDEVNGLISMYSTDENLIL SPLLGNVCFSSSQYSICFTLVSFAK IYADTFGDINYQEFAKRLWGDIYFN PKTRKFTKKAPTSSSQRSFVEFILE PLYKILAQVVGDVDTSLPRTLDELG IHLTKEELKLNIRPLLRLVCKKFFG EFTGFVDMCVQHIPSPKVGAKPKIE HTYTGGVDSDLGEAMSDCDPDGPLM CHTTKMYSTDDGVQFHAFGRVLSGT IHAGQPVKVLGENYTLEDEEDSQIC TVGRLWISVARYHIEVNRVPAGNWV LIEGVDQPIVKTATITEPRGNEEAQ IFRPLKFNTTSVIKIAVEPVNPSEL PKMLDGLRKVNKSYPSLTTKVEESG EHVILGTGELYLDCVMHDLRKMYSE IDIKVADPVVTFCETVVETSSLKCF AETPNKKNKITMIAEPLEKGLAEDI ENEVVQITWNRKKLGEFFQTKYDWD LLAARSIWAFGPDATGPNILVDDTL PSEVDKALLGSVKDSIVQGFQWGTR EGPLCDELIRNVKFKILDAVVAQEP LHRGGGQIIPTARRVVYSAFLMATP RLMEPYYFVEVQAPADCVSAVYTVL ARRRGHVTQDAPIPGSPLYTIKAFI PAIDSFGFETDLRTHTQGQAFSLSV FHHWQIVPGDPLDKSIVIRPLEPQP APHLAREFMIKTRRRKGLSEDVSIS KFFDDPMLLELAKQDVVLNYPMTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
